Lower lip cancers: analysis retrospectively for a period of 10-years

Alt dudak kanserleri: 10 yıllık retrospektif değerlendirme


Abstract views: 22 / PDF downloads: 21

Authors

  • Arif Türkmen Gaziantep Üniversitesi, Tıp Fakültesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Gaziantep
  • Ömer Berberoğlu Gaziantep Üniversitesi, Tıp Fakültesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Gaziantep
  • Mahmut Nuri Karatoprak Gaziantep Üniversitesi, Tıp Fakültesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Gaziantep
  • Mehmet Bekerecioğlu Gaziantep Üniversitesi, Tıp Fakültesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Gaziantep
  • Mehmet Mutaf Gaziantep Üniversitesi, Tıp Fakültesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı, Gaziantep

DOI:

https://doi.org/10.5455/GMJ-30-2011-35

Keywords:

Surgery, lip neoplasms, mortality

Abstract

Oral cavity cancers are reported to constitute 2-4% of all cancers. Being the most common among oral cancers, 95% of lip cancers are located on the lower lip, 4% on the upper lip and the remaining one percent at the commissure. The purpose of this article was to analyze retrospectively in lower lip cancer patients who were operated in our clinic. Between October 1999 and December 2009, 57 patients with lip cancer were analyzed retrospectively, with regards to their age, state of oral hygiene, etiological factors, nodal status at the first visit, period from the onset of symptoms to the patient’s first application to our clinic, follow-up period, neck dissection, postoperative radiotherapy and the TNM classification of the tumors. Hereby, we aimed at presenting our results and comparing them with the current data. The mean ages of the patients were 63.21 years and 70.17% were male and the remaining 29.83% were female. General oral care and hygiene was good in 8.77% and bad in 49.12% of males and good in 5.35% and bad in 19.29% of females. 52.64% of males and 5.35% of females were active smokers, and 44.5% of all patients had lymphadenomegaly at first admission. According to TNM classification, 43.88% of patients had T1, 33.32% had T2, 17.53% had T3 and 5.27% had T4 tumors. The tumors were excised with 1 cm surgical margins and 39 patients had cervical lymphatic dissection. 33.34% of the patients were given postoperative radiotherapy. During the first two years postoperatively, 89.48% of the patients visited the clinic on a regular basis, however, the intervals between visits increased thereafter. Lip cancers are commonly seen in males of advanced age. Following treatment, a long survival is evident in cases of early staged tumors. With this study, we aimed at comparing our results with existing data in the literature.

Metrics

Metrics Loading ...

References

Baker SR, Krause CJ. Carcinoma of the lip. Laryngoscope 1980;90(1):19-27.

Parkin DM, Laara E, Muir CS. Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1988;41(2):184-97.

Boring CC, Squries TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin 1994;44(1):7-26.

Howell RE, Wright BA, Dewar R. Trends in the incidence of oral cancer in Nova Scotia from 1983 to 1997. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95(2):205-12.

Landis SH, Murray T, Bolden S, Wingo PA. Cancer statistics, 1999. CA Cancer J Clin 1999;49(1):8-31.

Luce EA. Carcinoma of the lower lip. Surg Clin North Am 1986;66(1):3-11.

Karanfil H, Mısırlıoğlu A, Toksoy S, Karaca M, Bilgiç Mİ, Aköz T. Kliniğimizde alt dudak kanseri nedeniyle opere edilen hastaların retrospektif analizi. Turkiye Klinikleri J Dermatol 2009;19(4):179-83.

Öztürkcan S, Havlucu YD. Güneş hasarı etki mekanizması. Dermatose 2005;4(3):116-21.

Moore S, Johnson N, Pierce A, Wilson D. The epidemiology of lip cancer: a review of global incidence and etiology. Oral Disease 1999;5(3):185-95.

Hawk JIM. Cutaneous Photobiology. Chapter 21, In: Rook, Williams-Ebling, Textbook of Dermatology, 1992.

Chi AC. Epithelal Pathology-Lip Vermillion Carcinoma. In: Oral Pathology and Maxillofacial Pathology. 3rd edition, Neville BW, Damm DD, Allen CM, Bouquot JE (eds), Philadelphia, 2009, p.414-20.

Regezi JA, Sciubba JJ, Jordan RCK. Neoplasm-Lip Carcinoma. In: Oral Pathology, clinical pathological correlations. 4th edition Saunders, Elsevier, St. Louis, Missouri, 2008, p.52-4.

Jovanovic A, Schulten EA, Kostense PJ, Snow GB, van der Waal I. Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma. J Oral Pathol Med 1993;22(10):459-62.

Ogden GR, Wight AJ. Etiology of oral cancer: Alcohol. Br J Oral Maxillofac Surg 1998;36(4):247-51.

Shah JP. In: Head and Neck Surgery, Mosby-Wolfe, 2nd edition, London, 1996, p.143-66.

Gluckman J, Gullare P, Johnson J. In: Practical approach to the head and neck tumors. Raven Pres, 1st edition, New York, 1994, p.65-76.

Bardach J. Local flaps and free skin grafts in head and neck reconstruction. Mosby Year Book, St. Louis, 1st edition,1992, p.69-86.

Aston SJ, Beasley RW, Thorne CHM. Stile FL: Reconstructive surgery of the lips. Zide BM. In: Grabb and Smith’s Plastic Surgery. 5th edition, Lippincott-Raven, Philadelphia, 1997, p.483-500.

Zide B. Deformities of the lips and cheeks. In: McCarthy JG. Plastic Surgery. Vol 3, 2nd edition, Philadelphia, Pa: WB Saunders; 1990, p.2009-56.

Achauer BM, Erikson E, Guyuron B, Coleman III JJ, Russell RC, Vander Kolk CA. Reconstructive Lip Surgery. Coleman III JJ In: Plastic Surgery Indications, Operations, and Outcomes. Mosby, Vol 3, St. Louis, Behmand RA, Rees RS. 2000, p.1193- 209.

Downloads

Published

2023-05-01

How to Cite

Türkmen, A., Berberoğlu, Ömer, Karatoprak, M. N., Bekerecioğlu, M., & Mutaf, M. (2023). Lower lip cancers: analysis retrospectively for a period of 10-years: Alt dudak kanserleri: 10 yıllık retrospektif değerlendirme. European Journal of Therapeutics, 17(2), 73–76. https://doi.org/10.5455/GMJ-30-2011-35

Issue

Section

Original Articles