Comparison of the effectiveness of intralesional triamcinolone acetonide injection vs. incision and curettage techniques in the treatment of chalazion: Şalazyon tedavisinde lezyon içi triamsinolon asetonid enjeksiyonu ile insizyon ve küretaj yönteminin etkinliğinin karşılaştırılması

Ferhat Zorlu; Yusuf Koçluk; Emrah Mat; Ela Durucu

doi:10.5455/GMJ-30-42748

Authors

Ferhat Zorlu Tarsus State Hospital, Ophthalmology Clinic, Tarsus, Mersin
Yusuf Koçluk Gaziantep Dr. Ersin Arslan State Hospital, Ophthalmology Clinic, Şahinbey, Gaziantep
Emrah Mat Gaziantep Dr. Ersin Arslan State Hospital, Ophthalmology Clinic, Şahinbey, Gaziantep
Ela Durucu Gaziantep Dr. Ersin Arslan State Hospital, Ophthalmology Clinic, Şahinbey, Gaziantep

DOI:

https://doi.org/10.5455/GMJ-30-42748

Keywords:

Chalazion, incision and curettage, triamcinolone acetonide

Abstract

The aim of this study was to compare the effectiveness of intralesional triamcinolone acetonide injection with incision and curettage for the treatment of chalazion. Forty-six patients who were treated with conservative measures for at least 1 month without any healing were included into the study. Twenty-seven of them were treated with intralesional triamcinolone acetonide injection and 19 of them with incision and curettage via conjunctival approach. Regression of chalazion was observed in 24 (88%) of 27 patients who were injectedintralesional triamcinolone acetonide, and 18 (95%) of 19 patients who were applied incision and curettage. No statistical difference was seen between the success rate of these two treatment options. There was not any complication in patients who were treated with incision and curettage but local depigmentation was seen in one patient (3.7%) who was treated with triamcinolone acetonide at the second month at follow-up. This depigmentation spontaneously disappeared at the 4th month. As a result in terms of success and complication ratios, effectiveness and reliability of these two methods were found similar in the treatment of chalazion.

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References

Özçetin H. Gözkapağı Hastalıkları. Klinik Göz Hastalıkları. 1. baskı. Bursa. Nobel Tıp Kitabevleri. 2003;6.

Hoşal BM. Göz kapağının İnflamatuvar Hastalıkları ve Tedavisi. Göz kapakları. Oküloplasti: Gözyaşı sistemi, Gözkapağı, Orbita. Ed. Türk Oftalmoloji Derneği. Türk Oftalmoloji Derneği Eğitim Yayınları. 1. Baskı. Bursa. Papyrus. 2003;116-7.

Kanski JJ. Göz Kapağı Hastalıkları. Klinik Oftalmoloji. Çeviri Ed.: Orağlı KM, 4. Baskı, İstanbul. Nobel Tıp Kitabevi. 2001;12-13.

Lee JJ, Lin LY, Hsieh SW, Chang TA, Jou ST, Liu CC, et al. Successful treatment of Kasabach-Merritt phenomenon with intralesional corticosteroid injections: a case series. Int J Trichology 2012;4(4):265-70.

Samimi DB, Alabiad CR, Tse DT. An anatomically based approach to intralesional corticosteroid injection for eyelid capillary hemangiomas. Ophthalmic Surg Lasers Imaging 2012;43(3):190-5.

Sardesai VR, Prasad S, Agarwal TD. A study to evaluate the efficacy of various topical treatment modalities for alopecia areata. Ann Plast Surg 2012;69(6):627-32.

Alpay A, Uğurbaş SH, Uğurbaş SC. Şalazyon tedavisinde tek doz cilt altı steroid enjeksiyonunun etkinliği. Türkiye Klinikleri J Ophthalmol 2012;21(3):132-6.

Chung CF, Lai JS, Li PS. Subcutaneous extralesional triamcinolone acetonide injection versus conservative management in the treatment of chalazion. Hong Kong Med J 2006;12(4):278-81.

Ho SY, Lai JS. Subcutaneous steroid injection as treatment for chalazion: prospective case series. Hong Kong Med J 2002;8(1):18-20.

Ben Simon GJ, Huang L, Nakra T, Schwarcz RM, McCann JD, Goldberg RA. Intralesional triamcinolone acetonide injection for primary and recurrent chalazia: is it really effective? Ophthalmology 2005;112(5):913-7.

Ahmad S, Baig MA, Khan MA, Khan IU, Janjua TA. Intralesional corticosteroid injection vs surgical treatment of chalazia in pigmented patients. J Coll Physicians Surg Pak 2006;16(1):42-4.

Pavicić-Astalos J, Iveković R, Knezević T, Krolo I, Novak-Laus K, Tedeschi-Reiner E, et al. Intralesional triamcinolone acetonide injection for chalazion. Acta Clin Croat 2010;49(1):43-8.

Ben Simon GJ, Rosen N, Rosner M, Spierer A. Intralesional triamcinolone acetonide injection versus incision and curettage for primary chalazia: a prospective, randomized study. Am J Ophthalmol 2011;151(4):714-8.

Prasad S, Gupta AK. Subconjunctival total excision in the treatment of chronic chalazia. Indian J Ophthalmol 1992;40(4):103-5.

Yıldırım N. Kortikosteroid Glokomu. Glokomun Klinik Şekilleri. Glokom. Ed. Turaçlı ME, Önol M, Yalvaç IS. 1. baskı. Ankara. SFN Televizyon Tanıtım Tasarım Yayıncılık. 2003;106.

Ramot Y, Nyska A. Drug-induced thrombosis – experimental, clinical, and mechanistic considerations. Toxicol Pathol 2007;35(2):208-25.

Ullian ME. The role of corticosteriods in the regulation of vascular tone. Cardiovasc Res 1999;41(1):55-64.

Thomas EL, Laborde RP. Retinal and choroidal vascular occlusion following intralesional corticosteroid injection of a chalazion. Ophthalmology 1986;93(3):405-7.

Hosal BM, Zilelioglu G. Ocular complication of intralesional corticosteroid injection of a chalazion. Eur J Ophthalmol 2003;13(9-10):798-9.

Al-Mahdi H. Iris depigmentation: an unusual complication of intralesional corticosteroid injection for capillary hemangioma. Middle East Afr J Ophthalmol 2010;17(1):100- 2.

Yağci A, Palamar M, Eğrilmez S, Sahbazov C, Ozbek SS. Anterior segment ischemia and retinochoroidal vascular occlusion after intralesional steroid injection. Ophthal Plast Reconstr Surg 2008;24(1):55-7.

Goldberg RA. Orbital steroid injections. Br J Ophthalmol 2004;88(11):1359-60.

Herschler J. Intractable intraocular hypertension induced by repository triamcinolone acetonide. Am J Ophthalmol 1972;74(3):501-4.

Venkatesan P, Fangman WL. Linear hypopigmentation and cutaneous atrophy following intra-articular steroid injections for de Quervain's tendonitis. J Drugs Dermatol 2009;8(5):492-3.

Patrocinio TG, Loredo BA, Arevalo CE, Patrocinio LG, Patrocinio JA. Complications in blepharoplasty: how to avoid and manage them. Braz J Otorhinolaryngol 2011;77(3):322- 7.