Resolution of Intracoronary Thrombus with Tirofiban Infusion: A Case Report
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https://doi.org/10.58600/eurjther.2010-16-3-1230-archKeywords:
Myocardial infarction, Tirofiban infusionAbstract
A 27 year-old man presented with chest pain lasting for fourteen-hour duration. The patient had electrocardiographic evidence of subacute anterior wall myocardial infarction. Coronary angiography revealed total occlusion of the left anterior descending coronary artery. Tirofiban infusion was administered for 48 hours. Then, coronary angiography showed intraluminal filling defects due to a massive thrombus in the proximal segment of the left anterior descending coronary artery. We present a case of effective thrombolysis with tirofiban in young myocardial infarction case.
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The RESTORE Investigators. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation. 1997;96: 1445- 1453.
Akdemir R, Uyan C. Dissolution of a huge spontaneous coronary artery thrombus with a new antiplatelet agent and coronary angioplasty. International Journal of Cardiology. 2003;89:87-9.
Jayasundera TG, Feldman DN, Marmur JD. Tirofiban- induced coronary thrombolysis. J Invasive Cardiol. 1999; 11:138-40.
Williams MS, Coller BS, Vaanaanen HJ, et al. Activation of platelets in platelet-rich plasma by rotablation is speeddependent and can be inhibited by abciximab. Circulation. 1998; 98:742-748.
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