Some Metabolic Functions and Metabolism of Selenium and its relations with Vitamin E: [Selenyumun Bazı Fizyolojik İşlevleri Metabolizması ve E Vitamini ile Arasındaki İlişkiler]

A. Ziya Karakılçık; Mesut Aksakal

doi:10.58600/eurjther-199342-1111-x

Authors

A. Ziya Karakılçık Harran Ünv.Tıp Fakültesi Fizyoloji Anabilim Dalı Yrd.Doç.Dr.
Mesut Aksakal Fırat Ünv. Veteriner Fakültesi Fizyoloji Anabilim Dalı Doç.Dr.

DOI:

https://doi.org/10.58600/eurjther-199342-1111-x

Keywords:

Selenium, Vitamin E, Glutathione Peroxidase, Metabolism

Abstract

Selenium (Se) concentrations in the animal tissues vary according to the tissue and the amount and chemical form of Se in diet. in cattle and sheep Se concentrations rank in the order kidney, Iiver, heart, skeletal muscle and adipose tissue. Se like other elements, has a bimodal effect. At normal concentrations, Se is an essential trace element necessary for growth in man and animals. However, ıntake of high concentrations of Se can show toxic effects; ingestion of very low concentrations of this trace element results in Se-deficiency sympthoms in man and animals. The main physiological function of Se is as a component of the enzyme glutathione peroxidase. GSH-Px activity is very important for physiological functions of the liver, heart, skelatal muscle and erythrocytes.

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