Determination of in Vitro Susceptibilities of Candida Strains Isolated From Clinical Specimens as Pathogen to Systemic Antifungal Agents

[Klinik Örneklerden Patojen Etken Olarak İzole Edilen Candida Suşlarının Sistemik Etkili Antifungal Ajanlara Duyarlılıkları]


Abstract views: 188 / PDF downloads: 59

Authors

  • Hüseyin Gün GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD Bşk. Doç.Dr.
  • Mustafa Özyurt GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD. Dr.
  • Tuncer Haznedaroğlu GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD. Yrd.Doç.Dr.
  • Mehmet Baysallar GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD. Yrd.Doç.Dr.

DOI:

https://doi.org/10.58600/eurjther-199342-1095-x

Keywords:

Candida, antifungal agents, susceptibility

Abstract

In this study, susceptibilities of 50 Candida strain isolated and identified from clinical specimens as pathogen to systemic antifungal agents including amphotericin-B, flucanozole, ketocanozole and miconazole nitrate using Macro Dilution method and results were discussed in a view of literature data.

Metrics

Metrics Loading ...

References

Freeman BA.:Medical Mycology the Pathogenic Fungi and the Pathogenic Actinomychetes. Burrows Textbook of Microbiology 22 th ed. W.B. Saunders Company, 1985. 874-937.

Kasımoğlu Ö., Aktan G.:1990-91 Döneminde Çeşitli Muayene Maddelerinden İnfeksiyon Etkeni Olarak İzole Edilen Mayalar. Ankem Dergisi, 6:(No.2), 1992 (80)(7. Türk Ankem Kongre Bildirisi).

Pfizer International Inc.:Candida, The Growing Problem. New York, 1987, 1-34.

Bodey GP.:Candidiasis in Cancer Patients.Am.J.Med.77:(Suppl.4D), 13-19, 1984.

Bodey GP. ,Anaissie EJ:Opportunistic Fungal Infections;A ma jor Problem in Immunocompromised Patients. The Am.Journal of Medicine, 1984, 1-16.

Gold JWM.:Opportunistic Fungal lnfections in Patients with Neoplastic Disease. Thc Am.Journal of Medicine, 76:458-463, March 1984.

Tümbay E., İnci R.:Antifungal Kemoterapi Türk Mikrobiyoloji Cemiyeti Yayınlan, No:17, 16-35, 1992.

Warren NG., Shadomy HJ,;Yeasts of Medical lmportance. Manual of Clinical Microbiology 5 th, Edition, (Ed.s.) Balows, A., Hausler, W.J., Hermann, K.L., Isenberg, H,D., Shadomy, H.J., Am,Soc, for Miy, Washington D.C., 1991, 617-629.

Tiimbay ll,:Sistemik Etkili Yeni Bir Antifungal Kemoterapötik Flukonazol, infeksiyon Dergisi (Turkish Journal of lnfection), 3:(l), (1989 Ek baskı Seri no:1), 1989.

Dreizen S,:Oral Candidiasis. The Am, Journal of Medicine, 30:28-33, Oct.l984.

Nicholas RO., Kerridge D, :Drug Resistance in the Opportunistic; Pathogens C.albicans and C.glabrata, Journal of Antimicrobial Chemotherapy, 18:Suppl. ll,39-49, 1986.

Saag MS,, Dismukes WE.: Minireview, Azole Antifungal Agents, Emphasis on New Triatzoles, Antimicrobial Agent and Chemotherapy, 32:(1), 1·8, Jan., 1988.

Shadomy S., Ingroff EA: In Vitro and In Vivo Evaluation of Antifungal Agents, Evr. J. Clin. Microbial.Infect.Dis., 8:(4), 352-361, April, 1989.

Yüce K: Antibiyotikler ve İnfeksiyon Hastalıklarında Tedavi Prensipleri, Ege Üniversitesi Tıp Fakültesi Yayınları, İzmir, Bornova, 1988. S. 87-90.

Pfaller MA, Burmeister L., Bartlett MS, Rinaldi MG.:Multicenter Evaluation of Four Methods of Yeast lnokulum Preparation. Joumal of Clinical Microbiology, 26:143-1441, Aug., 1988.

Shadomy S., Pfaller MA,:Laboratory Studies with Antifungal Agents Susceptibility Tests and Quantitation in Body Fluids, Manual of Clinicııl Microbiology 5 th. Edition, (Eds.) Balows, A,, Hausler, W.J., Hermann K.L., Isenberg, H,D., Shadomy, H,J,, Am,Soc,for Microbiology, Washington D.C. 1991, 1173-1181.

Galgiani JN., Reiser J., Brass C., Espinel IA., Gordon MA, and Kerkering TM,:Comparison of Relative Susceptibilities of Candida Species to Three Antifungal Agents as Detemined by Unstandardized Methods. Antimicrobial Agentsand Chemotherapy, 31:(9), 1343-1347, Sept. 1987,

Merz WG,:Susceptibility Testing of Medically Important Fungi. Adv,Exp. Med,Biol., 202:127-134, 1986.

Galgiani JN.:Mini Review Antifungal Agents and Chemotherapy, 31:(12), 1867-1870, Des., 1987.

Galgiııni JN., Mcintyre KA.:ln Vitro Susceptibilities of Yeasts to A New Antifungal Triazole SCH 39304, Effeçts of Test Conditions and Relııtion to in Vivo Efficacy. Antimicrobial Agents and Chemotherapy, 33:(7), 1095-1100, July 1989.

Kobayashl GS., Odds FC.:Current Perspectives on Antifungal Susceptibility Testing. Focus on Fluconazole First Printing, Scientific Therapeutics İnforrnation, ine., 1989, 1-26.

Ingroff AE., Kerkering TM., Goldsan PR., Shadomy S.:Comparison Study of Broth Macrodilution and Microdilution Antifungal Susceptibility Tests. Journal of Clinlcal Microbiology, 29:1089-1094, June, 1991.

Anaissie E., Paetanick V. and Dodey GP.:Fluconazole Susceptibility Testing of C.albicans: Microtiter Method that is lndependent of lnoculum Size, Temperature and Time of Ceading. Antimicrobial Agents and Chemotherapy, 35:1641-1646, Aug. 1991.

PfalJer MA., Rinaldi MG., Galgiani JN., Bartlett MS., Body BA., lnroff EA., Fromtling RA, HalJ GS., Huaghes CE., Odds FC. and Sugar AM.:Collaborative Investigation of Variables in Susceptibility, Testing of Yeasts. Antimicrobial Agents and Chemotherapy, 34:1648-1654, Sept., 1990.

Galgiani JN.,Calhoun DL.:Analysis of pH and Buffer Effects on Flucytosine Activity in Broth Dilution Susceptibility Testing of Candida albicans in Two Synthetic Media. Antimicrobial Agents and Chemotherapy, 26:(3), 364-367, Sept. 1984.

Gordon MA., Lapa EW. and Passero PG.:Improved Method for Azole Antifungal Susceptibility Testing. Joumal of Oinical Microbiology, 26:1874-1884, Sept., 1988.

Radetsky M., Wheeler RC., Roe MH. and Todd JK.:Microtiter Broth Dilution Method far Yeast Susceptibility Testing with Validation by Clinical Outcome. Journal of Clinical Microbiology, 24:600-606, Oct., 1986.

Rogers TE. and Galgiani JN.:Activity of Fluconazole (UK 49, B 58) and Ketoconazole, Against C.albicans in Vitro and in Vivo. Antimicrobial Agents and Chemotherapy, 30:(3), 418-422, Sept., 1986.

Ghannoum MA., Sharif HF ., Charreer H.:Sensitivity of Clinical Yeast lsolates in Kuwait Against a Number of Antifungal Agents. Mykosen, 27:(8), 402-410, 1984.

Ahearn DG., Ghohn Mc.Ms.:ln Vitro Susceptibilities of Sucrose-Negative C.tropicalis, C.lusitaniac and C.norvegensis to Amphotericin-B, 5-Fluorocytosine, Miconazole and Ketoconazole. Joumal of Oinical Microbiology, 19:412-416, March 1984.P.

Surarit R., Maxwell GS.:The Effects of Azole and Polyene Antifungals on the Plazma Membrane Enzymes of C.albicans. Joumal of Medical and Veterinary Mycology, 25:403-413, 1987.

Downloads

Published

1993-06-01

How to Cite

Gün, H., Özyurt, M., Haznedaroğlu, T., & Baysallar, M. (1993). Determination of in Vitro Susceptibilities of Candida Strains Isolated From Clinical Specimens as Pathogen to Systemic Antifungal Agents: [Klinik Örneklerden Patojen Etken Olarak İzole Edilen Candida Suşlarının Sistemik Etkili Antifungal Ajanlara Duyarlılıkları]. European Journal of Therapeutics, 4(2), 181–192. https://doi.org/10.58600/eurjther-199342-1095-x

Issue

Section

Original Articles