Glioblastoma after radiotherapy for childhood acute  lymphoblastic leukemia: Review: Çocukluk çağı akut lenfoblastik lösemi radiyoterapisi sonrası gelişen  gliyoblastoma: Derleme

Abdurahman Kuzhan

doi:10.5455/GMJ-30-1787

Authors

Abdurahman Kuzhan Department of Radiation Oncology, Gaziantep University, School of Medicine

DOI:

https://doi.org/10.5455/GMJ-30-1787

Keywords:

Chemotherapy, glioblastoma, leukemia, radiation

Abstract

Induction of neoplasia after therapeutic irradiation is well recognized. The development of the glioblastoma has been documented less frequently in association with radiation therapy. Pediatric patients with acute lymphoblastic leukemia are more susceptible to radiation-induced complications than adult patients. Post radiation glioblastomas in childhood acute lymphoblastic leukemia have poor prognosis. Treating postradiation glioblastomas are challenging for pediatric neuro-oncologists because of their more aggressive course than primary glioblastomas. To improve survival ratios and quality of life new researches are required in this treatment field. The goal of this review is to discuss the possible risk factors for radiation-induced tumorgenesis and histopathological characteristics

Metrics

Metrics Loading ...

References

Marcus KJ, Sandlund JT. Pediatric Leukemias and Lymphomas. In: Gunderson LL, Teper JE, ed. Clinical Radiation Oncology. 3rd ed. Philadelphia: Elsevier, 2012; 1479–88.

Chung CK, Stryker JA, Cruse R, Vannuci R, Towfighi J. Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphocytic leukemia. Cancer 1981; 47(11): 2563–66.

Bien E, Stachowicz-Stencel T, Szalewska M, Krawczyk M, Synakiewicz A, Dubaniewicz-Wybieralska M, et al. Poor-risk high-grade gliomas in three survivors of childhood acute lymphoblastic leukaemia--an overview of causative factors and possible therapeutic options. Childs Nerv Syst 2009; 25(5): 619–26.

Borgmann A, Zinn C, Hartmann R, Herold R, Kaatsch P, Escherich G, et al. Secondary malignant neoplasms after intensive treatment of relapsed acute lymphoblastic leukaemia in childhood. Eur J Cancer 2008; 44(2): 257–68.

Donson AM, Erwin NS, Kleinschmidt-DeMasters BK, Madden JR, Addo-Yobo SO, Foreman NK. Unique molecular characteristics of radiation-induced glioblastoma. J Neuropathol Exp Neurol 2007; 66(8): 740–9.

Fontana M, Stanton C, Pompili A, Amadori S, Mandelli F, Meloni G, et al. Late multifocal gliomas in adolescents previously treated for acute lymphoblastic leukemia. Cancer 1987; 60(7): 1510–8.

Menon R, Muzumdar D, Shah A, Goel A. Glioblastoma multiforme following cranial irradiation and chemotherapy for acute lymphocytic leukaemia. Report of 3 cases. Pediatr Neurosurg 2007; 43(5): 369–74.

Muzumdar DP, Desai K, Goel A. Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphoblastic leukaemia: a case report. Neurol India 1999; 47(2): 142–4.

Relling MV, Rubnitz JE, Rivera GK, Boyett JM, Hancock ML, Felix CA, et al. High incidence of secondary brain tumours after radiotherapy and antimetabolites. Lancet 1999; 354(9172): 34–9.

Salvati M, D'Elia A, Melone GA, Brogna C, Frati A, Raco A, Delfini R. Radio-induced gliomas: 20-year experience and critical review of the pathology. J Neurooncol 2008; 89(2): 169–77.

Sanders J, Sale GE, Ramberg R, Clift R, Buckner CD, Thomas ED. Glioblastoma multiforme in a patient with acute lymphoblastic leukemia who received a marrow transplant. Transplant Proc 1982; 14(4): 770–4.

Shah KC, Rajshekhar V. Glioblastoma multiforme in a child with acute lymphoblastic leukemia: case report and review of literature. Neurol India 2004; 52(3): 375–7.

Shapiro S, Mealey J Jr. Late anaplastic gliomas in children previously treated for acute lymphoblastic leukemia. Pediatr Neurosci 1989; 15(4): 176–80.

Symss NP, Pande A, Chakravarthy MV, Ramamurthi R. Glioblastoma multiforme occurring in a child with acute lymphoblastic leukemia. J Pediatr Neurosci 2006; 1(2): 63–5.

Walter AW, Hancock ML, Pui CH, Hudson MM, Ochs JS, Rivera GK, et al. Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children’s Research Hospital. J Clin Oncol 1998; 16(12): 3761–67.

Yaris N, Erduran E, Celep F, Yavuz M, Reis A. Secondary glioblastoma multiforme with a new translocation t(3; 3)(q21;q26) following treatment of acute lymphoblastic leukaemia. Turk J Paediatr 2005; 47(1): 98–9.

Nishio S, Morioka T, Inamura T, Takeshita I, Fukui M, Sasaki M, et al. Radiation-induced brain tumours: potential late complications of radia¬tion therapy for brain tumours. Acta Neurochir (Wien) 1998; 140(8): 763–70.

Mahvash M, Hugo HH, Maslehaty H, Mehdorn HM, Stark AM. Glioblastoma multiforme in children: report of 13 cases and review of the literature. Pediatr Neurol 2011; 45(3): 178–80.

Perry A, Schmidt RE. Cancer therapy-associated CNS neuropathology: an update and review of the literature. Acta Neuropathol 2006; 111(3): 197–212.

Mann I, Yates PC, Ainslie JP. Unusual case of double primary orbital tumour. Br J Ophthalmol 1953; 37(12): 758–62.

Modan B, Mart H, Braidtz D, Sternit ZR, Levin SG. Radiation induced head and neck tumours. Lancet 1974; 1(7852): 277–9.

Bassal M, Mertens AC, Taylor L, Neglia JP, Greffe BS, Hammond S, et al. Risk of selected subsequent carcinomas in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol 2006; 24(3): 476–83.

Neglia JP, Meadows AT, Robison LL, Kim TH, Newton WA, Ruymann FB, et al. Second neoplasms after acute lymphoblastic leukemia in childhood. N Engl J Med 1991; 325(1): 1330–36.

Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL. Sarcoma arising in irradiated bone; report of 11 cases, 1948. Cancer 1998; 82(1): 8–34.

Mothersill C, Seymour CB. Radiation-induced bystander effects – implications for cancer. Nat Rev Cancer 2004; 4(2): 158–64.

Widel M, Przybyszewski WM, Cieslar-Pobuda A, Saenko YV, Rzeszowska-Wolny J. Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation. Mutat Res 2012; 731(1-2): 117–24.

Mancuso M, Pasquali E, Leonardi S, Rebessi S, Tanori M, Giardullo P. Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo. Oncogene 2011; 30(40): 4601–08.

Nygaard R, Garwicz S, Haldorsen T, Hertz H, Jonmundsson GK, Lanning M, Moe PJ. Second malignant neoplasms in patients treated for childhood leukemia. A population-based cohort study from the Nordic countries. The Nordic Society of Pediatric Oncology and Hematology (NOPHO). Acta Paediatr Scand 1991; 80(12): 1220–8.

Löning L, Zimmermann M, Reiter A, Kaatsch P, Henze G, Riehm H, Schrappe M. Secondary neoplasms subsequent to Berlin-Frankfurt-Münster therapy of acute lymphoblastic leukemia in childhood: significantly lower risk without cranial radiotherapy. Blood 2000; 95(9): 2770–5.

Waber DP, Shapiro BL, Carpentieri SC, Gelber RD, Zou G, Dufresne A, et al. Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber Cancer Institute Consortium Protocol 87–01. Cancer 2001; 92(1): 15–22.

Rosso P, Terracini B, Fears TR, Jankovic M, Fossati Bellani F, Arrighini A, et al. Second malignant tumors after elective end of therapy for a first cancer in childhood: a multicenter study in Italy. Int J Cancer 1994; 59(4): 451–6.

Reddick WE, Glass JO, Helton KJ, Langston JW, Xiong X, Wu S, Pui CH. Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate. AJNR Am J Neuroradiol 2005; 26(5): 1263–9.

Braunstein S, Nakamura JL. Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk. Front Oncol 2013;3:73. doi: 10.3389/fonc.2013.00073. eCollection 2013.

Kleinerman RA. Radiation-sensitive genetically susceptible pediatric sub-populations. Pediatr Radiol 2009; 39 Suppl 1: S27-S31.

Kelly KM, Perentesis JP. Polymorphisms of drug metabolizing enzymes and markers of genotoxicity to identify patients with Hodgkin’s lymphoma at risk of treatment-related complications. Ann Oncol 2002; 13 Suppl 1: 34-9.

Bigner SH, McLendon RE, Fuchs H, McKeever PE, Friedman HS. Chromosomal characteristics of childhood brain tumors. Cancer Genet Cytogenet 1997; 97(2): 125–34.

Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, et al. Molecular genetic alterations in radiation-induced astrocytomas. Am J Pathol 1999; 154(5): 1431–8.