Ligneous gingivitis: a case report

Lignöz gingivitis: olgu sunumu


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Authors

  • Hasan Gündoğar Gaziantep Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Gaziantep
  • Kemal Üstün Gaziantep Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Gaziantep
  • Ufuk Sezer Gaziantep Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Gaziantep
  • Kamile Erciyas Gaziantep Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Gaziantep

DOI:

https://doi.org/10.5455/GMJ-30-2013-130

Keywords:

Gingivitis, ligneous, ligneous conjunctivitis, periodontal disease

Abstract

Ligneous gingivitis, also known as destructive membranous periodontal disease is a rare periodontal condition. While first case was published by Frimodt-Moller at 1973, ligneous conjunctivitis was first described in 1847 by Bouisson. It is characterized by nodular gingival enlargement with ulcerations. Usually conjunctival and gingival lesions were observed together and have same histopathological changes. A 32 month-old female patient with ligneous conjunctivitis, was referred to Gaziantep University, Faculty of Dentistry, Department of Periodontology clinic with the diagnosis of spread gingival enlargement at the mandible and maxilla. These gingival enlargements were painless, hyperemic, nodular, and woody-like and covered by pseudo membrane. Radiographic evaluation showed normal alveolar bone and no attachment loss. Hematological analyses showed an increase in white blood cells, and increase in lymphocytes but decrease in neutrophils. As far as we know this is the youngest case reporting ligneous gingivitis after Frimodt-Mollers’ case. Although most of the case reports focused on histopathological change and level of plasminogen in these patients, up to now exact information about pathogenesis of ligneous gingivitis and conjunctivitis is not available in the literature. Question of the researchers about how to manage and effectively treat this disease remains unclear.

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References

Gunhan O, Avci A, Dereci O, Akgun S, Celasun B. Extensive fibrin accumulation and accompanying epithelial changes in the pathogenesis of ligneous mucosal disease (ligneous periodontitis). Am J Dermatopathol 2012;34(1):35-40.

Schuster V, Seregard S. Ligneous conjunctivitis. Surv Ophthalmol 2003;48(4):369-88.

Tefs K, Gueorguieva M, Klammt J, Allen CM, Aktas D, Anlar FY, et al. Molecular and clinical spectrum of type I plasminogen deficiency: a series of 50 patients. Blood 2006;108(9):3021-6.

Tefs K, Georgieva M, Seregard S, Tait CR, Luchtman-Jones L, Ziegler M, et al. Characterization of plasminogen variants in healthy subjects and plasminogen mutants in patients with inherited plasminogen deficiency by isoelectric focusing gel electrophoresis. Thromb Haemost 2004;92(2):352-7.

Schuster V, Seidenspinner S, Zeitler P, Escher C, Pleyer U, Bernauer W, et al. Compound-heterozygous mutations in the plasminogen gene predispose to the development of ligneous conjunctivitis. Blood 1999;93(10):3457-66.

Colucci M, D'Aprile AM, Italia A, Gresele P, Morser J, Semeraro N. Thrombin activatable fibrinolysis inhibitor (TAFI) does not inhibit in vitro thrombolysis by pharmacological concentrations of t-PA. Thromb Haemost 2001;85(4):661-6.

Frimodt-Moller J. Conjunctivitis ligneosa combined with a dental affection. Report of a case. Acta Ophthalmol (Copenh) 1973;51(1):34-8.

Sivolella S, De Biagi M, Sartori MT, Berengo M, Bressan E. Destructive membranous periodontal disease (ligneous gingivitis): a literature review. J Periodontol 2012;83(4):465-76.

Chi AC, Prichard E, Richardson MS, Rasenberger KP, Weathers DR, Neville BW. Pseudomembranous disease (ligneous inflammation) of the female genital tract, peritoneum, gingiva, and paranasal sinuses associated with plasminogen deficiency. Ann Diagn Pathol 2009;13(2):132-9.

Gunhan O, Gunhan M, Berker E, Gurgan CA, Yildirim H. Destructive membranous periodontal disease (ligneous periodontitis). J Periodontol 1999;70(8):919-25.

Kurtulus I, Kazmi B, Lewis MP, Solakoglu S, Schuster V, Scully C, et al. Altered functional activity patterns of fibroblasts related to periodontitis by systemic plasminogen deficiency (ligneous periodontitis). Quintessence Int 2011;42(7):601-9.

Baltacioglu E, Akalin FA, Topaloglu E, Sukuroglu E, Cobanoglu U. Ligneous periodontitis and gingival antioxidant status: report of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;104(6):803-8.

Baykul T, Bozkurt Y. Destructive membranous periodontal disease (ligneous periodontitis): a case report and 3 years follow-up. Br Dent J 2004;197(8):467-8.

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Published

2023-05-03

How to Cite

Gündoğar, H., Üstün, K., Sezer, U., & Erciyas, K. (2023). Ligneous gingivitis: a case report: Lignöz gingivitis: olgu sunumu. European Journal of Therapeutics, 19(2), 128–130. https://doi.org/10.5455/GMJ-30-2013-130

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Section

Case Reports