Biomechanic comparative of cancellous autograft with xenograft originating from bovine enriched with autogen bone marrow

Abstract

Autologous cancellous bone grafts contain osteoconductive, osteoinductive and osteogenic elements. No alternate graft material contains alt of these three components for the regeneration of the bone. However, autogenous grafting is associated with several complications, bone graft substitutes have been used in a wide range of orthopaedic pathologic condition. Xenografts (heterografts) are one of these alternatives. Although there are some histological and radiological studies conceming bone grafts of bovine origin, we could not find any comparative biomechanical counterparts. in this study we aim to compare cancellous autograft with xenograft originating from bovine enriched with autogen bone marrow regarding the biomechanical endurance within the duration of the fracture union. Therefore, radiological and histological studies will be reviewed in addition to biomechanical study. Eighteen dogs with a mean age of 14 months (range 12 to, 16 months) were included in this study). All of the operations were performed under general anesthesia and Unilab Surgibone® grafts wem us.ed for xenografts. Autogen grafts were used from iliac crests and standart fracture were tried to be formed on fibulas. After being convinced of the fracture union radiologically, the segments which were ,derived from fibulas were tested by using a biomechanic test Monsanto Tensorneter which has ±200g. sensitivity was used for mechanical tests. A meaningful difference were not able to found after statistical comparison of mechanical strength of the new bones which were formed by the two bone grafts (p>0.05,). lf you carry out the results of this, study to the cıinical practice, it rıııay be assumed that weight bearing can be permit ted at the same time for both groups.