Correlation of colour doppler findings with spermiogram parameters in varicocele  patients

Ahmet Erbağcı; Kemal Sarıca; Faruk Yağcı; Özcan Özalpat; Tuğrul Pınar

doi:10.58600/eurjther.2000-11-1-2-909-arch

Authors

Ahmet Erbağcı Gaziantep Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı, Gaziantep
Kemal Sarıca Gaziantep Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı, Gaziantep
Faruk Yağcı Gaziantep Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı, Gaziantep
Özcan Özalpat Gaziantep Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı, Gaziantep
Tuğrul Pınar Gaziantep Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı, Gaziantep

DOI:

https://doi.org/10.58600/eurjther.2000-11-1-2-909-arch

Keywords:

Colour flow doppler ultrasonograpy, lnfertility, varicocele

Abstract

Aim: To evaluate the relationship between varicocele and male subfertility in the light of objective methods including Colour Flow Doppler Sonography (CFDS) and seminal analysis.

Material and methods: Between 1996 and the end of 2000, 147 patients complaining with scrotal pain and/or swelling, infertility were evaluated with respect to CFDS finding and that of spermiogram data. in addition to complete physical examination each patient was undergone at least two seminal analysis and conventional sonography. However, CFDS was also applied in cases with suspicion of subclinical varicocele at infertility status. Seminal analysis were counted with Makler Chamber. The results were comparatively evaluated with Pearson correlation test, Wilcoxon test and Student-t test.

Results: CFDS was found as reliable and noninvasive enough in searching the relation between infertility and subclinical varicocele. The sperm motility and concentration were found to have good corelation with venous back flow in these patients (p<0.05). Additionally these parameters were returned to normal limits perfectly after surgical correction of yaricocele in infertile group (p<0.05).

Conclusion: Regarding diagnosis of the lesion, as a more sensitive and non-invasive technique, CFDS has been shown to detect scrotal varicosities which are too subtle to identify on physical examination. Again documentation of actual retrograde venous flow rather than venous dilatation made this technique superior to conventional gray scale sonography.

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References

Mazzoni G, Fiocca G, Minucci S, Pieri S, Paolicelli D, Morucci M, et al. Varicocele: A multidisiplinary approach in children and adolescent. JUrol 1999; 162:1755-1758.

Sigmund G, Gall H, Bahren W. Stop-type and shunt-type varicoceles: venographic finding. Radiology 1987; 163:105-110.

Mncallum SW, Girardi SK, Goldstein M. Varicocele. in Vaughan ED, Perlmutter AP, Lue TF, Goldstein M (eds). Atlas of Clinical Urology:lmpotance and lnfertility (1st ed). Philadelphia, Current Medicine 1999: 111-120.

Sigman M, Howards SS. Male infertility, in: Walsh PC, et al(eds); Champbell's Urology (7th ed), Philedelphia, Sounders, 1998: 1287-1320.

Tumer TT, Lopez TJ. Effects of experimental varicocele require neither adrenal contribution nor venous reflux. J Urol 1989; 142: 1372-1375.

lbrahim AA, Hamada TA, Moussa MM. Effects of varicocele on sperm respiration and metabolism. Andrologia 1981; 13:253-259.

Sharma RK, Agarwall A. Role of reactive oxygen species in male infertility. Urology 1996; 48: 489-494.

Su LM, Goldstein M, Schlegel PN. The effect of varicocelectomy on serum testosterone levels in infertile men with varicoceles. J Urol 1995; 154:1752-1755.

Swerdloff RS, Walsh PC. Pituitary and gonadal hormones in patients with varicocele. Fertil Steril 1975; 26:1006-1012.

Harrison RM, Lewis RW, Roberts JA. Testicular blood flow and fluid dynamics in monkeys with surgically induced varicocele. J Androl 1983; 4:256- 260.

Saypol DC, Howards SS, Tumer TT, Miller ED. Influence of surgically induced varicocele on testicular blood flow, tempreture and histology in adult rats and dogs J Clin Invest 1981; 68:39-45.

Skoog SJ, Roberts K.P, Goldstein M, Pryor JL. The adolescent varicocele: what's new with an old problem in young patients? Pediatrics 1997; 100:112- 121.

Chehval MJ, Purcell MH. Determination of semen parameters over time in men with untreated varicoceles: evidences of progresive testicular demage. Fertil Steri 1992; 57:174-177.

Barbalias GA, Liatsikos EN, Nikiforidas G, Siablis D. Treatment ofvaricocele for male infertility: A comparative study evaluating currently used approaches Eur Urol 1998; 34:393-398.

Cameron DF, Syndle FE. Ultrastructural surface characteristics of seminiferous tubtiles from men with varicocele. Andrologia 1982; 14:425-433.

Glezerman M. Varicocele: questions and answers on etiology, pathophysiology and management. in: Colpi GM, Balema M (eds) Treating Male Infertility. (1st ed). Switzerland, Karger,1994:87-98.

Sigman M and Jarrow JP. Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol,. 1997; 158:605-607.

Shikone T, Billig H, Hsueh A. Experimentally induced cryptorchidism increases apoptosis in rat testis. Biol Reprod 1994; 51 :865-872.

Ando A, Giacchetto C, Beraldi E, Panno ML, Lombardi A, Sposato G, et al. The influence of age 0'1 leydig cell function in patients with varicocele. lnt J Androl, 1984; 7:104-118.

Jarow JP, Ogle SR, Eskew LA. Seminal improvement following repair of ultrasound detected subclinical varicoceles J Urol 1995; 155:1287-1290.

Hendin BN, Kolettis PN, Sharma RK, Thomas AJ, Agarwal A. Varicocele is associated with elevated sperınatozoal reactive oxygen species production and diminised seminal plasma antioxidant capasity. J Urol 1999; 161:1831-1834.

Lund L, Emst E, Sorensen HT, Oxlund H. Biomechanical properties of the intemal spermatic vein in the normal population and patients with left- sided varicocele testis. Eur Urol 1998; 33:233-237.

Brandel RA, ShihuaLi P, Goldstein M. Varicocelectomy. Urol Clin North Am 1999; 7:145- 154.

Schlesinger MH, Wilets IF, Nahler HM. Treatment outcome after varicocelectomy. Urol Clin North Am 1994; 21:517-529.

Pryor JL, Howards SS. Varicocele. in: Tanagho EA, Lue TF, Mcclure RD (eds). Contemporary management of Impotance and Infertility (l st ed). Baltimore, Williams & Wilkins 1988:247-264

Scherr D, Goldstein, Comparison of bilateral versus unilateral varicocelectomy in men with palpable bilateral varicoceles. J Urol 1999; 162:85-88.

Okuyama A, Nakamura M, Namiki M. Surgical repair of varicocele at puberty: preventive treatment for fertility improvement. J Urol 1988; 139:562-564.

Meacham RB, Townsend RR, Rademacher D, Drose JA. The incidence of varicoceles in the general population when evaluated by physical examination, gray scale sonography and color doppler sonography, J Urol 1994; 151:1535-1538.

Jarrow JP, Cobum M. Incidence ofvaricoceles in men with primary and secondary infertility. Urology 1996; 47:73-76.

Segenreich E, lsrailov S, Shmuele J, Niv E, Baniel J, Livine P. Evaluation of the relationship between semen parameters, pregnancy rate of wives of infertile men with varicocele and gonadotropin- releasing hormone test before and after varicocelectomy. Urology 1998; 52:853-857.

Segenreich E, Israilov S, Shmuele J, Niv E, Servadio C. Correlation between semen parameters and retrograde flow into the pampiniform plexus before and after varicocelectomy. Eur Urol 1997; 32:310-314.

Pierik FH, Vreeburg TM, Stijnen TH, Van Roijen JH, Dohle GR, Lameris JS, et al. Improvement of sperm count and motility after ligation of varicocele detected with colour doppler ultrasonography. lnt J Andrology 1998; 21 :256-260.

Abdulmaaboud MR, Shokeir AA, Farage Y, El- rahman AA, El-Rakhawy MM, Mutabagani H. Treatment of varicocele: A comparative study of conventional open surgery, percutaneous retrograde sclerotherapy and laparascopy Urology 1998; 52:294- 300.