The relationship of carpal tunnel syndrome and mean platelet volume in geriatric patients

Geriatrik hastalarda karpal tünel sendromu ile ortalama trombosit hacminin ilişkisi


Abstract views: 136 / PDF downloads: 43

Authors

  • Ahmet Tutoğlu Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Ahmet Boyacı Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Özcan Kocatürk Department of Neurology, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Suna Sarıkaya Department of Neurology, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Mahmut Kul Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Emel Yiğit Karakaş Department of Internal Medicine, Faculty of Medicine, Harran University, Şanlıurfa, Turkey
  • Alparslan Yetişgin Şanlıurfa Mehmet Akif İnan Education and Research Hospital, Şanlıurfa, Turkey

DOI:

https://doi.org/10.5455/GMJ-30-153778

Keywords:

Carpal tunnel syndrome, mean platelet volume

Abstract

The aim of this study was to examine the relationship between idiopathic carpal tunnel syndrome (CTS) and mean platelet volume (MPV) in patients older than 65 years old. The study included 48 patients, 92 hands (45 right/47 left) from 8225 patients who were consulted to electroneuromyography (ENMG) laboratory in January 2010 to December 2013. ENMG data, whole blood cell, erythrocyte sedimentation rate, C-reactive protein (CRP) levels of all patients were noted. In patient group MPV levels were significantly high (P=0.014). Although CRP levels were significantly elevated in patients, all CRP levels were in normal range. As a result, in patients older than 65 years increased MPV levels may be associated with CTS etiology and increased risk of cardiovascular disease.

Metrics

Metrics Loading ...

References

de Krom MC, Knipschild PG, Kester AD, Thijs CT, Boekkooi PF, Spaans F. Carpal tunnel syndrome: prevalence in the general population. J Clin Epidemiol 1992;45(4):373-6.

Keir PJ, Rempel DM. Pathomechanics of peripheral nerve loading. Evidence in carpal tunnel syndrome. J Hand Ther 2005;18(2):259-69.

Albers JW, Brown MB, Sima AA, Greene DA. Frequency of median mononeuropathy in patients with mild diabetic neuropathy in the early diabetes intervention trial (EDIT). Tolrestat Study Group For Edit (Early Diabetes Intervention Trial). Muscle Nerve 1996;19(2):140-6.

Bland JD. Carpal tunnel syndrome. Curr Opin Neurol 2005;18(5):581-5.

Amirfeyz R, Gozzard C, Leslie IJ. Hand elevation test for assessment of carpal tunnel syndrome. J Hand Surg Br 2005;30(4):361-4.

Sandhaus LM, Meyer P. How useful are CBC and reticulocyte reports to clinicians? Am J Clin Pathol 2002;118(5):787-93.

Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996;7(2):157-61.

Bath P, Algert C, Chapman N, Neal B. Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke 2004;35(3):622-6.

Endler G, Klimesch A, Sunder-Plassmann H, Schillinger M, Exner M, Mannhalter C, et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 2002;117(2):399- 404.

Kisacik B, Tufan A, Kalyoncu U, Karadag O, Akdogan A, Ozturk MA, et al. Mean platelet volume (MPV) as an inflammatory marker in ankylosing spondylitis and rheumatoid arthritis. Joint Bone Spine 2008;75(3):291-4.

Karabudak O, Ulusoy RE, Erikci AA, Solmazgul E, Dogan B, Harmanyeri Y. Inflammation and hypercoagulable state in adult psoriatic men. Acta Derm Venereol 2008;88(4):337- 40.

Balbaloglu O, Korkmaz M, Yolcu S, Karaaslan F, Beceren NG. Evaluation of mean platelet volume (MPV) levels in patients with synovitis associated with knee osteoarthritis. Platelets 2014;25(2):81-5.

Wagner DD, Burger PC. Platelets in inflammation and thrombosis. Arterioscler Thromb Vasc Biol 2003;23(12):2131-7.

Sprague DL, Elzey BD, Crist SA, Waldschmidt TJ, Jensen RJ, Ratliff TL. Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by plateletderived membrane vesicles. Blood 2008;111(10):5028-36.

Smyth SS, McEver RP, Weyrich AS, Morrell CN, Hoffman MR, Arepally GM, et al. Platelet functions beyond hemostasis. J Thromb Haemost 2009;7(11):1759-66.

Kocer A, Yaman A, Niftaliyev E, Duruyen H, Eryilmaz M, Kocer E. Assessment of platelet indices in patients with neurodegenerative diseases: mean platelet volume was increased in patients with Parkinson's disease. Curr Gerontol Geriatr Res 2013;2013:986254.

Canpolat F, Akpinar H, Eskioglu F. Mean platelet volume in psoriasis and psoriatic arthritis. Clin Rheumatol 2010;29(3):325-8.

Joshi P, Lele V. Lighting the tunnel: FDG PET/CT findings leading to incidental diagnosis of carpal tunnel syndrome. Clin Nucl Med 2014;39(1):e78-9.

Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des 2011;17(1):47-58.

Park JH, Kim SN, Han SM, Cheon KY, Han SW, Kim JY, et al. Carotid intima-media thickness in patients with carpal tunnel syndrome. J Ultrasound Med 2013;32(10):1753-7.

Downloads

Published

2023-05-02

How to Cite

Tutoğlu, A., Boyacı, A., Kocatürk, Özcan, Sarıkaya, S., Kul, M., Karakaş, E. Y., & Yetişgin, A. (2023). The relationship of carpal tunnel syndrome and mean platelet volume in geriatric patients: Geriatrik hastalarda karpal tünel sendromu ile ortalama trombosit hacminin ilişkisi. European Journal of Therapeutics, 20(2), 182–185. https://doi.org/10.5455/GMJ-30-153778

Issue

Section

Original Articles