Mitral annular calcification – An overview

Mitral anuler kalsifikasyon - Derleme


Abstract views: 64 / PDF downloads: 18

Authors

  • Gökhan Altunbaş Department of Cardiology, Kilis State Hospital, Kilis, Turkey
  • Vedat Davutoğlu Department of Cardiology, University of Gaziantep, Faculty of Medicine, Gaziantep, Turkey

DOI:

https://doi.org/10.5455/GMJ-30-49323

Keywords:

Cardiovascular events, mitral annular calcification, stroke

Abstract

Calcification of the mitral annulus has long been considered as a benign condition. However, recent investigations have shed a light on this condition. According to the severity of the disease, the result may be regurgitation or rarely stenosis of the mitral valve. In addition to the local effects, mitral annular calcification is considered as a surrogate for systemic inflammation, widespread calcifications and cardiovascular risk factors. Treatment is considered when calcification is severe enough to cause hemodynamic effects or is suspected to be a source of systemic embolization. Different surgical techniques are employed according to the localization and severity of the calcium deposition, the function of the valves and overall patient condition.

Metrics

Metrics Loading ...

References

Kanjanauthai S, Nasir K, Katz R, Rivera JJ, Takasu J, Blumenthal RS, et al. Relationships of mitral annular calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2010; 213(2):558-62.

Sharma R, Pellerin D, Gaze DC, Mehta RL, Gregson H, Streather CP, et al. Mitral annular calcification predicts mortality and coronary artery disease in end stage renal disease. Atherosclerosis 2007;191(2):348-54.

Kurtoğlu E, Korkmaz H, Aktürk E, Yılmaz M, Altaş Y, Uçkan A. Association of mitral annulus calcification with highsensitivity C-reactive protein, which is a marker of inflammation. Mediators Inflamm 2012;2012:606207.

Roberts WC. The senile cardiac calcification syndrome. Am J Cardiol 1986;58(6):572-4.

Fox CS, Parise H, Vasan RS, Levy D, O’Donnell CJ, D’Agostino RB, et al. Mitral annular calcification is a predictor for incident atrial fibrillation. Atherosclerosis 2004; 173(2): 291-4.

Atar S, Jeon DS, Luo H, Siegel RJ. Mitral annular calcification: a marker of severe coronary artery disease in patients under 65 years old. Heart 2003;89(2):161-4.

Asselbergs FW, Mozaffarian D, Katz R, Kestenbaum B, Fried LF, Gottdiener JS, et al. Association of renal function with cardiac calcifications in older adults: the cardiovascular health study. Nephrol Dial Transplant 2009:24(3);834-40.

Kohsaka S, Jin Z, Rundek T, Boden-Albala B, Homma S, Sacco RL, et al. Impact of mitral annular calcification on cardiovascular events in a multiethnic community: the Northern Manhattan Study. JACC Cardiovasc Imaging 2008:1(5);617-23.

Ziyrek M, Tayyareci Y, Yurdakul S, Şahin ŞT, Yıldırımtürk Ö, Aytekin S. Association of mitral annular calcification with endothelial dysfunction, carotid intima-media thickness and serum fetuin-A: an observational study. Anadolu Kardiyol Derg 2013;13(8):752-8.

Kurtoglu E, Akturk E, Korkmaz H, Ataş H, Çuğlan B, Pekdemir H. Impaired heart rate variability in patients with mitral annular calcification: an observational study. Anadolu Kardiyol Derg 2013;13(7):668-74.

Benjamin EJ, Plehn JF, D’Agostine RB, Belanger AJ, Comai K, Fuller DL, et al. Mitral annular calcification and the risk of stroke in an elderly cohort. N Eng J Med 1992;327(6):374-9.

De Marco M, Gerdts E, Casalnuova G, Migliore T, Wachtell K, Boman K, et al. Mitral annular calcification and incident ischemic stroke in treated hypertensive patients: the LIFE study. Am J Hypertens 2013;26(4):567-73.

Celik A, Davutoglu V, Sarica K, Erturhan S, Ozer O, Sari I, et al. Relationship between renal stone formation, mitral annular calcification and bone resorption markers. Ann Saudi Med 2010;30(4):301-5.

Davutoglu V, Yilmaz M, Soydinc S, Celen Z, Turkmen S, Sezen Y, et al. Mitral annular calcification is associated with osteoporosis in women. Am Heart J 2004;147(6):1113-6.

Burnside JW, Desanctis RW. Bacterial endocarditis on calcification of the mitral annulus fibrosus. Ann Intern Med 1972;76(4):615-8.

Feindel CM, Tufail Z, David TE, Ivanov J, Armstrong S. Mitral valve surgery in patients with extensive calcification of the mitral annulus. J Thorac Cardiovasc Surg 2003;126(3):777- 82.

Downloads

Published

2023-05-02

How to Cite

Altunbaş, G., & Davutoğlu, V. (2023). Mitral annular calcification – An overview: Mitral anuler kalsifikasyon - Derleme. European Journal of Therapeutics, 20(2), 120–122. https://doi.org/10.5455/GMJ-30-49323

Issue

Section

Review Articles

Categories