Mesenteric lymphadenitis, pancytopenia, and acute brucellosis: Mezenterik lenfadenit, pansitopeni ve akut bruselloz

Muhammed Sait Dağ; İbrahim Türkbeyler; Azize Gökhan; Musa Aydınlı; Mehmet Cemil Savaş; Abdurrahman Kadayıfçı

doi:10.5455/GMJ-30-2011-41

Authors

Muhammed Sait Dağ Gaziantep Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Gaziantep
İbrahim Türkbeyler Gaziantep Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gaziantep
Azize Gökhan Gaziantep Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları Anabilim Dalı, Gaziantep
Musa Aydınlı Gaziantep Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Gaziantep
Mehmet Cemil Savaş Gaziantep Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Gaziantep
Abdurrahman Kadayıfçı Gaziantep Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Gaziantep

DOI:

https://doi.org/10.5455/GMJ-30-2011-41

Keywords:

Acute brucellosis, mesenteric lymphadenitis, pancytopenia

Abstract

Brucellosis is a zoonotic infection caused by gram (-) Brucella species and involves multiple organ systems. It usually presents with fever and constitutional symptoms, but atypical presentations may also occur. Acute brucellosis presenting with pancytopenia and abdominal pain due to mesenteric lymphadenitis have been published as case reports. A 71-year-old woman admitted to our clinic with severe abdominal pain mimicking acute abdomen, fever, constipation and weight loss for last three weeks. In complete blood count, there was serious pancytopenia. Although Wright agglutination test was negative, Brucella species were isolated in blood culture. Combined treatment of rifampicin 600 mg/day and doxycycline 200 mg/day was started. There were mesenteric enlarged lymph nodes detected in the computerized tomography and the abdominal pain was thought to be related with this mesenteric lymphadenitis. The clinical and laboratory findings were dramatically improved with the treatment and it was continued for six weeks. In conclusion, although the presentation of acute brucellosis with mesenteric lymphadenitis and pancytopenia is rare, it must be considered in patients such in endemic areas.

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