Applications of Photobiomodulation Therapy in Oral Medicine—A Review


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Authors

  • Mohamed Faizal Asan Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India https://orcid.org/0000-0001-9747-1914
  • G Subhas Babu Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India https://orcid.org/0000-0001-9383-7886
  • Renita Lorina Castelino Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India https://orcid.org/0000-0002-8696-549X
  • Kumuda Rao Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India https://orcid.org/0000-0002-6214-1381
  • Vaibhav Pandita Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), Mangalore, India https://orcid.org/0000-0003-3163-5300

DOI:

https://doi.org/10.5152/eurjther.2021.20080

Keywords:

Lasers, mucositis, orofacial pain, photobiomodulation therapy, temporomandibular disease

Abstract

Applications of photobiomodulation (PBM) in dentistry have been of great interest in the recent times. It can both stimulate and suppress biological effects. The property of PBM contributes to the analgesic, anti-inflammatory, and wound healing effects. Photobiomodulation therapy (PBMT) has a wide variety of clinical applications that include wound healing, prevention of cellular death, promotion of repair mechanisms, reduction of inflammation, pain relief, etc. Hence, it is being used effectively in the field of oral medicine and has shown promising results in the management of oral mucosal lesions, orofacial pain, and other orofacial ailments without much significant adverse effects. The purpose of this review is to discuss the applications of PBMT in the field of oral medicine.

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References

Ga´spa´r L. Professor Endre Mester, the father of photobiomodulation. J Laser Dent. 2009;17(3):146-148.

Xu YY, Liu TC, Cheng L. Photobiomodulation process. Int J Photoenergy. 2012; Article ID: 374861.

Mandel A, Hamblin MR. A renaissance in low-level laser (light) therapy-LLLT. Photonics Lasers Med. 2012;1(4):231-234.

Parker S. Low-level laser use in dentistry. Br Dent J. 2007;202(3):131-138.

Leal-Junior EC, Lopes-Martins RA´ , Bjordal JM. Clinical and scientific recommendations for the use of photobiomodulation therapy in

exercise performance enhancement and post-exercise recovery: Current evidence and future directions. Braz J Phys Ther.

;23(1):71-75.

Heiskanen V, Hamblin MR. Photobiomodulation: Lasers vs. light emitting diodes?. Photochem Photobiol Sci. 2018;17(8):1003-1017.

Sun G, Tuner J. Low-level laser therapy in dentistry. Dent Clin North Am. 2004;48(4):1061-1076.

Pinheiro AL, Cavalcanti ET, Pinheiro TI, et al. Low-level laser therapy is an important tool to treat disorders of the maxillofacial

region. J Clin Laser Med Surg. 1998;16(4):223-226.

Bjordal JM, Couppe C, Ljunggren AE. Low level laser therapy for tendinopathy. Evidence of a dose–response pattern. Phys Ther Rev.

;6(2):91-99.

Kahraman SA. Low-level laser therapy in oral and maxillofacial surgery. Oral Maxillofac Surg Clin North Am. 2004;16(2):277-288.

Hamblin MR, Demidova TN. Mechanisms of low level light therapy—An introduction. Proc SPIE. 2006;6140:61001-61012.

Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng.

;40(2):516-533.

Huang YY, Chen AC, Carroll JD, Hamblin MR. Biphasic dose response in low level light therapy. Dose Response. 2009;7(4):358-383.

Pandeshwar P, Roa MD, Das R, Shastry SP, Kaul R, Srinivasreddy MB. Photobiomodulation in oral medicine: A review. J Investig Clin

Dent. 2016;7(2):114-126.

Antonic´ R, Brumini M, Vidovic´ I, Urek MM, Glazˇar I, Pezelj-Ribaric´ S. The effects of low level laser therapy on the management of

chronic idiopathic orofacial pain: Trigeminal neuralgia, temporomandibular disorders and burning mouth syndrome. Med Fluminensis.

;53(1):61-67.

Khalighi HR, Anbari F, Beygom Taheri J, Bakhtiari S, Namazi Z, Pouralibaba F. Effect of low-power laser on treatment of orofacial pain. J Dent Res Dent Clin Dent Prospects. 2010;4(3):75-78.

Chow R, Armati P, Laakso EL, Bjordal JM, Baxter GD. Inhibitory effects of laser irradiation on peripheral mammalian nerves and

relevance to analgesic effects: A systematic review. Photomed Laser Surg. 2011;29(6):365-381.

Zokaee H, Zahmati AH, Mojrian N, Boostani A, Vaghari M. Efficacy of low-level laser therapy on orofacial pain: A literature review. Adv Hum Biol. 2018;8(2):70.

Zand N. Non-thermal, non-ablative CO2 laser therapy (NACLT): A new approach to relieve pain in some painful oral diseases. CO2

laser-optimization and application. InTech. 2012;387-414.

Ross G, Ross A. Photobiomodulation: An invaluable tool for all dental specialties. J Laser Dent. 2009;17(3):117-124.

Boras VV, Juras DV, Rogulj AA, Panduric DG, Verzak Z, Brailo V. Applications of low level laser therapy. In Motamedi MHK (ed.): A

Textbook of Advanced Oral and Maxillofacial Surgery. Croatia: InTech, 2013:327-339.

Anschau F, Webster J, Capra MEZ, de Azeredo da Silva ALF, Stein AT. Efficacy of low-level laser for treatment of cancer oral mucositis:

A systematic review and meta-analysis. Lasers Med Sci. 2019;34(6):1053-1062.

Marı´n-Conde F, Castellanos-Cosano L, Pacho?n-Iban˜ ez J, Serrera-Figallo MA, Gutierrez-Perez JL, Torres-Lagares D.

Photobiomodulation with low-level laser therapy reduces oral mucositis caused by head and neck radio-chemotherapy: Prospective randomized controlled trial. Int J Oral Maxillofac Surg. 2019;48(7):917-923.

El Mobadder M, Farhat F, El Mobadder W, Nammour S. Photobiomodulation therapy in the treatment of oral mucositis, dysphagia,

oral dryness, taste alteration, and burning mouth sensation due to cancer therapy: A case series. Int J Environ Res Public Health.

;16(22):4505.

Lanzafame RJ. Photobiomodulation: An enlightened path emerges. Photomed Laser Surg. 2013;31(7):299-300.

Genot-Klastersky M, Paesmans M, Ameye L, et al. Retrospective evaluation of the safety of low-level laser

herapy/photobiomodulation in patients with head/neck cancer. Support Care Cancer. 2020;28(7):3015-3022.

Pezelj-Ribaric´ S, Kqiku L, Brumini G, et al. Proinflammatory cytokine levels in saliva in patients with burning mouth syndrome before

and after treatment with low-level laser therapy. Lasers Med Sci. 2013;28(1):297-301.

Spanemberg JC, Lo?pez Spangenberg J, de Figueiredo MA, Cherubini K, Salum FG. Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: A randomized, controlled trial. J Biomed Opt. 2015;20(9):098001.

Bardellini E, Amadori F, Conti G, Majorana A. Efficacy of the photobiomodulation therapy in the treatment of the burningmouth syndrome. Med Oral Patol Oral Cir Bucal. 2019;24(6):e787-e791.

Rodrigues JH, Marques MM, Biasotto-Gonzalez DA, et al. Evaluation of pain, jaw movements, and psychosocial factors in elderly individuals with temporomandibular disorder under laser phototherapy. Lasers Med Sci. 2015;30(3):953-959.

Sayed N, Murugavel C, Gnanam A. Management of temporomandibular disorders with low level laser therapy. J Maxillofac Oral

Surg. 2014;13(4):444-450.

Del Vecchio A, Floravanti M, Boccassini A, et al. Evaluation of the efficacy of a new low-level laser therapy home protocol in the

treatment of temporomandibular joint disorder-related pain: A randomized, double-blind, placebo-controlled clinical trial. Cranio.

;39(2):141-150.

Anand V, Gulati M, Govila V, Anand B. Low level laser therapy in the treatment of aphthous ulcer. Indian J Dent Res. 2013;24(2):267-270.

Al-Maweri SA, Kalakonda B, Al-Soneidar WA, Al-Shamiri HM, Alakhali MS, Alaizari N. Efficacy of low-level laser therapy in management

of symptomatic oral lichen planus: A systematic review. Lasers Med Sci. 2017;32(6):1429-1437.

Luke AM, Mathew S, Altawash MM, Madan BM. Lasers: A review with their applications in oral medicine. J Lasers Med Sci.

;10(4):324-329.

Stona P, da Silva Viana E, Dos Santos Pires L, Blessmann Weber JB, Floriani Kramer P. Recurrent labial herpes simplex in pediatric dentistry: Low-level laser therapy as a treatment option. Int J Clin Pediatr Dent. 2014;7(2):140-143.

Al-Maweri SA, Kalakonda B, AlAizari NA, et al. Efficacy of low-level laser therapy in management of recurrent herpes labialis: A

systematic review. Lasers Med Sci. 2018;33(7):1423-1430.

Gomes IO, De Morais HO, Chagas WP, et al. Treatment of mucous membrane pemphigoid with low-level laser therapy. Oral Surg

Oral Med Oral Pathol Oral Radiol. 2020;129(1):e26.

Cafaro A, Broccoletti R, Arduino PG. Low-level laser therapy for oral mucous membrane pemphigoid. Lasers Med Sci. 2012;27(6):1247-1250.

Gira˜o EvangelistaI´, Pontes Tabosa FB, Bezerra AV, de Arau?jo Neto EV Jr. Low-level laser therapy in the treatment of inferior alveolar

nerve paresthesia after surgical exercises of a complex odontoma. J Lasers Med Sci. 2019;10(4):342-345.

Ozen T, Orhan K, Gorur I, Ozturk A. Efficacy of low level laser therapy on neurosensory recovery after injury to the inferior alveolar

nerve. Head Face Med. 2006;2(1):3.

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Published

2021-06-28

How to Cite

Asan, M. F., Babu, G. S., Castelino, R. L., Rao, K., & Pandita, V. (2021). Applications of Photobiomodulation Therapy in Oral Medicine—A Review. European Journal of Therapeutics, 27(2), 177–182. https://doi.org/10.5152/eurjther.2021.20080

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Section

Review Articles