Massive Hepatosplenomegaly due to Uveal Melanoma Metastasis

Muhammed Sait Dağ; İbrahim Türkbeyler; İbrahim  Sarı; Seyithan Taysı; Abdurrahman  Kadayıfçı

doi:10.58600/eurjther.2011-17-1-759-arch

Authors

Muhammed Sait Dağ University of Gaziantep, Faculty of Medicine, Department of Gastroenterology, Gaziantep
İbrahim Türkbeyler University of Gaziantep, Faculty of Medicine, Department of Gastroenterology, Gaziantep
İbrahim Sarı University of Gaziantep, Faculty of Medicine, Department of Pathology, Gaziantep
Seyithan Taysı University of Gaziantep, Faculty of Medicine, Department of Biochemistry, Gaziantep
Abdurrahman Kadayıfçı University of Gaziantep, Faculty of Medicine, Department of Gastroenterology, Gaziantep

DOI:

https://doi.org/10.58600/eurjther.2011-17-1-759-arch

Keywords:

Uveal melanoma, liver metastasis, massive hepatosplenomegaly

Abstract

Uveal melanoma is a rare tumor which may cause to liver metastasis. We report a case of uveal melanoma which presents with severe abdominal pain and massive hepatosplenomegaly due to diffuse liver metastasis. The patient had a history of enucleation and ocular prosthesis for left eye more than 1 year. On physical examination the liver was palpable about 10 cm with a smooth and hard surface. The spleen was also palpable. Medical records of patient showed that he had an operation for uveal melanoma previously. Urine melanin was detected at the Thormahlen’s test. The liver biopsy confirmed the presence of a metastasis of malignant melanoma. Massive hepatosplenomegaly due to uveal melanoma is a rare clinical entity. The medical history of the patient is very important for suspicion of the underlying pathology.

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