Evaluation of Antibiotic Prophylaxis in the University of Gaziantep Medical Faculty Research Hospital Surgical Departments


Abstract views: 45 / PDF downloads: 28

Authors

  • Belgin Alaşehirli Gaziantep Üniversitesi, Tıp Fakültesi, Tıbbi Farmakoloji Anabilim Dalı, Gaziantep
  • Elif Oğuz Harran Üniversitesi, Tıp Fakültesi, Tıbbi Farmakoloji Anabilim Dalı, Şanlıurfa
  • Süda Tekin Koruk Harran Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları Anabilim Dalı, Şanlıurfa
  • İbrahim Koruk Harran Üniversitesi, Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, Şanlıurfa
  • İlkay Karaoğlan Gaziantep Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları Anabilim Dalı, Gaziantep
  • Özlem Yaylagül Çam Gaziantep Üniversitesi, Tıp Fakültesi, Araştırma ve Uygulama Hastanesi Enfeksiyon Kontrol Komitesi Hemşiresi, Gaziantep
  • A. Tuncay Demiryürek Gaziantep Üniversitesi, Tıp Fakültesi, Tıbbi Farmakoloji Anabilim Dalı, Gaziantep

DOI:

https://doi.org/10.58600/eurjther.2011-17-1-753-arch

Keywords:

Prophylactic antibiotic, surgical prophylaxis, wound infection

Abstract

The aim of this study is to evaluate the use of prophylactic antibiotics in surgery clinic of our hospital. A total of 101 patients underwent operation at the surgical clinics of Gaziantep University Medical Faculty Hospital on December 10, 2009 included to the study. A structured data form containing information about patients and used antibiotics completed by the nurse of hospital's infection control committee and her assistant. Patient selection was based on the classification of injury. All patient information forms were evaluated by infectious disease specialists using the surgical prophylaxis guide. A total of 128 antibiotics have been used for 101 patients, participated in the study. Prophylactic antibiotic selection were appropriate in 57.4% of all selected antibiotics (n = 58). The spectrums of 37.5% of single and dual used antibiotics were not appropriate. Besides, 35.2% of penetration and 73.2% of duration of use were not appropriate. In our study, most of the errors in surgical prophylaxis were seen in the duration of use. Besides, the unnecessary application and use of broad-spectrum antibiotics are seen. The wrong practices in surgical prophylaxis lead to unnecessary antibiotics treatment to the patients, development of resistance and also burden to the budget of the country.

Metrics

Metrics Loading ...

References

Talbot TR. Surgical site infectios and antimicrobial prophilaxis. In: Mandell GL, Bennett JE, Dolin R (Eds). Principles and Practice of Infectious Diseases. Seventh edition, Philadelphia, Churchill Livingstone, 2010. p.3891-904.

Burke JP. Infection control-a problem for patient safety. N Engl J Med 2003;348:651-6.

Martone WJ, Nichols RL. Recognition, prevetion, surveillance, and management of surgical site infections; Introduction to the problem and symposium overview. Clin Infect Dis 2001; 33(Suppl 2):67-8.

James M, Martinez EA. Antibiotics and perioperative infections. Best Pract Res Clin Anaesthesiol 2008;22(3):571-84.

De Lalla F. Perioperative antibiotic prophylaxis: a critical review. Surg Infect (Larchmt) 2006;7:37-9.

Özkurt Z. Cerrahi profilakside antibiyotik kullanımı. ANKEM Derg 2005;19(3):111-4.

Gagliotti C, Ravaglia F, Resi D, More ML. Quality of local guidelines for surgical antimicrobial prophylaxis. J Hosp Infect 2004;56(1):67-70.

Karadayı K, Turan M, Şen M. Genel cerrahide profilaktik antibiyotik kullanımı. Cumhuriyet Üniversitesi Tıp Fakültesi Derg 2002;25(1):38-42.

Classen DC, Evans RS, Pestotnik SL, Horn SD, Menlove RL, Burke JP. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med 1992;326(5):281-6.

Hoşoğlu S. Cerrahi profilakside problemler ve sistemimizdeki uygulamalar. ANKEM Derg 2004;18(Ek 2):185-7.

Kurçer Z, Oğuz E, Kurçer MA, Tacir A, Ünal B, Uzunköy A. Harran Üniversitesi Tıp Fakültesi Araştırma ve Uygulama Hastanesi'nde cerrahi profilaktik antibiyotik uygulamalarının değerlendirilmesi. Klimik Derg 2006;19(2):46-8.

Bratzler DW, Houck PM. Antimicrobial prophylaxis for surgery: An advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis 2004;38:1706-15.

Gagliotti C, Ravaglia F, Resi D, Moro ML. Quality of local guidelines for surgical antimicrobial prophylaxis. J Hosp Infect 2004;56:67-70.

Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 1999;20(4):250-78.

Page CP, Bohnen JM, Fletcher JR, McManus AT, Solomkin JS, Wittmann DH. Antimicrobial prophylaxis for surgical wounds. Guidelines for clinical care. Arch Surg 1993;128:79-88.

Ertuğrul MB, Özgün H, Saylak MÖ, Sayım N. Bir üniversite hastanesi cerrahi servislerinde antibiyotik kullanımı ve maliyeti: Bir günlük nokta prevalansı çalışması. Klimik Derg 2009;22(2):44-7.

Downloads

Published

2011-01-01

How to Cite

Alaşehirli, B., Oğuz, E., Koruk, S. T., Koruk, İbrahim, Karaoğlan, İlkay, Çam, Özlem Y., & Demiryürek, A. T. (2011). Evaluation of Antibiotic Prophylaxis in the University of Gaziantep Medical Faculty Research Hospital Surgical Departments. European Journal of Therapeutics, 17(1), 11–14. https://doi.org/10.58600/eurjther.2011-17-1-753-arch

Issue

Section

Original Articles