Thyroglossal Duct Cysts: A Clinico-Surgical Experience of 100 Cases

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Thyroglossal, cysts, fistula, midline neck swelling, sistrunk


Objective: Thyroglossal duct cysts occur if a thyroglossal duct does not disappear after the complete embryonic development of the thyroid gland and becomes cystic. This study aimed to examine the clinical features, physical examination findings, and treatments of 100 patients who underwent surgery with the diagnosis of thyroglossal duct cyst in the midline of the neck. Methods: This was a retrospective study based on anamnesis forms, clinical examinations, and radiographic imaging of 100 cases diagnosed with and operated on for thyroglossal duct cyst in our clinic. Results: Of the 100 patients, 53 were males and 47 were females, with their ages ranging from 1 to 62 (mean 18.15 6 15.8) years. The most common complaints were neck swelling (88%) and intermittent discharge (11%). Concomitant infection and fistula were present in 52 and 30% patients, respectively. The most common localization observed in 67 (67%) patients was in the infrahyoid area. Infection and abscess were observed in six cases (6%) during the early post-operative period. Papillary thyroid carcinoma, in addition to the cyst, was found in four cases. Recurrence was observed in three (3.7%) of the 81 primary cases. Sistrunk procedure was employed in all study patients. Conclusion: Thyroglossal duct cyst is the most common observed congenital mass in the neck. It must be considered in the differential diagnosis of patients admitted due to discharge and swelling in the midline of the neck. The generally accepted treatment of thyroglossal duct cysts is surgery, with Sistrunk surgery being the most appropriate surgical technique owing to its low complication and recurrence rate. It should also be known that these cysts have a risk of malignant transformation. The most common post-operative complications observed in our study were infection and abscess.


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Thompson LDR, Herrera HB, Lau SK. A clinicopathologic series of 685 thyroglossal duct remnant cysts. Head Neck Pathol.


Chou J, Walters A, Hage R, et al. Thyroglossal duct cysts: Anatomy, embryology and treatment. Surg Radiol Anat. 2013;35(10):875-881.

Soni S, Poorey VK, Chouksey S. Thyroglossal duct cyst, variation in presentation, our experience. Indian J Otolaryngol Head Neck Surg.


Narayana Moorthy S, Arcot R. Thyroglossal duct cyst more than just an embryological remnant. Indian J Surg. 2011;73(1):28-31.

Jackie C, Andrew W, Robert H, et al. Thyroglossal duct cysts: Anatomy, embryology and treatment. Surg Radiol Anat. 2013;35:875-

de Tristan J, Zenk J, Ku¨ nzel J, et al. Thyroglossal duct cysts: 20 years’ experience (1992–2011). Eur Arch Otorhinolaryngol.


Alpay HC, Kaygusuz I, Karlidag T, Keles E, Yalcin S, Dabak H. Tiroglossal duktus kist ve fistu¨ lleri: 32 vakalık bir inceleme. Firat Tip

Dergisi. 2007;12:287-289.

Mondin V, Ferlito A, Muzzi E, et al. Thyroglossal duct cyst: Personal experience and literature review. Auris Nasus Larynx. 2008;35(1):11-25.

Ac¸ıkalın RM, Hacı C, Bayram AA, Gezginadam Z. Tiroglossal duktus kist ve fistu¨ llerindeki klinik sonuc¸larımız. Med Bull Haseki. 2016;54:94-96.

Alatsakis M, Drogouti M, Tsompanidou C, et al. Invasive thyroglossal duct cyst papillary carcinoma: A case report and review of the

literature. Am J Case Rep. 2018;19:757-762.

Gioacchini FM, Alicandri-Ciufelli M, Kaleci S, et al. Clinical presentation and treatment outcomes of thyroglossal duct cysts: A

systematic review. Int J Oral Maxillofac Surg. 2015;44:119-126.

Sistrunk WE. The surgical treatment of cysts of the thyroglossal tract. Ann Surg. 1920;71(2):121-122.2.

Oomen KP, Modi VK, Maddalozzo J. Thyroglossal duct cyst and ectopic thyroid: Surgical management. Otolaryngol Clin North Am.


Righini CA, Hitter A, Reyt E, et al. Thyroglossal duct surgery: Sistrunk procedure. Eur Ann Otorhinolaryngol Head Neck Dis.


Ren W, Zhi K, Zhao L, et al. Presentations and management of thyroglossal duct cyst in children versus adults: A review of 106 cases.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111(2):e1-e6.

Simon LM, Magit AE. Impact of incision and drainage of infected thyroglossal duct cyst on recurrence after sistrunk procedure.

Arch Otolaryngol Head Neck Surg. 2012;138(1):20-24.

Pradeep PV, Jayashree B. Thyroglossal cysts in a pediatric population: Apparent differences from adult thyroglossal cysts. Ann Saudi

Med. 2013;33(1):45-48.

Abuabara A, Baratto Filho F, Fuzza RF. Thyroglossal duct cyst. South Braz Dent J. 2010;7(2):244-246.

O¨ ztu¨ rk K, Yaman H, Akbay E, Keles B, Arbag˘ H, O¨ zer B. Tiroglossal kist cerrahi sonuc¸larımız. Genel Tıp Dergisi. 2005;15:117-120.

Rohof D, Honings J, Theunisse HJ, et al. Recurrences after thyroglossal duct cyst surgery: Results in 207 consecutive cases and

review of the literature. Head Neck. 2015;37(12):1699-1704.

Tarcoveanu E, Niculescu D, Elena CA, et al. Thyroglossal duct cysts. J Chirurgie Iasi. 2009;5(1):45-51.

Islam O. Thyroglossal duct cyst imaging. 2013.

Yaman H, Durmaz A, Arslan HH, Ozcan A, Karahatay S, Gerek M. Thyroglossal duct cysts: Evaluation and treatment of 49 cases.

B-ENT. 2011;7(4):267-271.

Yalc¸ın S . Boyun kitleleri. In Çelik O (ed.): Kulak Burun Bog˘az Hastalıkları ve Bas Boyun Cerrahisi. _Istanbul: Turgut Yayıncılık, 2002:860-889.

Gupta P, Maddalozzo J. Preoperative sonography in presumed thyroglossal duct cysts. Arch Otolaryngol Head Neck Surg.


Bsoul SA, Flint DJ, Terezhalmy GT, et al. Thyroglossal duct cyst. Quintessence Int. 2003;34:156-157.

Adeniran JO, Durell J, Lakhoo K. Neck: Cysts, sinuses, and fistulas. In Pediatric Surgery. Cham: Springer, 2020:395-404.

Flageole H, Laberge JM, Ngyuyen LT, et al. Reoperation for cysts of the thyroglossal duct. Can J Surg. 1995;38:225-229.

Ein SH, Shandling B, Stephens CA, et al. The problem of recurrent tyhroglossal duct remnants. J Pediatr Surg. 1984;19:437-439.

Dedivitis RA, Camargo DL, Peixoto GL, et al. Thyroglossal duct: A review of 55 cases. J Am Coll Surg. 2002;194:274-277.




How to Cite

Aytac¸, I., & Tunç, O. (2021). Thyroglossal Duct Cysts: A Clinico-Surgical Experience of 100 Cases. European Journal of Therapeutics, 27(2), 118–122.



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