Radiological Findings of the Primary Female Urethral Malignant Melanoma: A Rare Case Report

Serkan Öner; Gülnur Erdem; Zeynep Maraş Özdemir; Ali Güneş; Serkan Ünlü

doi:10.5152/EurJTher.2018.495

Authors

Serkan Öner Department of Radiology, Karabük University School of Medicine, Karabük https://orcid.org/0000-0002-7802-880X
Gülnur Erdem Department of Radiology, İnönü University School of Medicine, Malatya https://orcid.org/0000-0003-2200-8620
Zeynep Maraş Özdemir Department of Radiology, İnönü University School of Medicine, Malatya https://orcid.org/0000-0003-1085-8978
Ali Güneş Department of Urology, İnönü University School of Medicine, Malatya https://orcid.org/0000-0002-2343-6056
Serkan Ünlü Department of Radiology, İnönü University School of Medicine, Malatya https://orcid.org/0000-0001-7535-0812

DOI:

https://doi.org/10.5152/EurJTher.2018.495

Keywords:

Female urethra, radiological findings, urethral malignant melanoma

Abstract

Primary malignant melanomas of the female urethra are rare tumors with poor prognosis. Biopsy of the detected urethral mass was performed in a 71-year-old woman who presented with hematuria and voiding dysfunction. No other localized lesions were detected. The patient was diagnosed with primary malignant melanoma of the urethra according to the histopathologic and immunohistochemical findings. Immunohistochemical staining revealed that the tumor cells were immunoreactive for vimentin, HMB-45, S-100, and Melan-A. The present study aimed to present radiological findings of very rare primary urethral malign melanoma with histopathologic correlation and to review the relevant literature.

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References

Bhutani N, Kajal P, Pawar D. Primary malignant melanoma of the female urethra: Report of a rare neoplasm of the urinary tract. Int J Surg Case Rep 2017; 41: 319-22.

Akbas A, Akman T, Erdem MR, Antar B, Kilicarslan I, Onol SY. Female urethral malignant melanoma with vesical invasion: a case report. Kaohsiung J Med Sci 2010; 26: 96-8.

Oliva E, Quinn TR, Amin MB, Eble JN, Epstein JI, Srigley JR, et al. Primary malignant melanoma of the urethra: a clinicopathologic analysis of 15 cases. Am J Surg Pathol 2000; 24: 785-96.

Gupta R, Bhatti SS, Dinda AK, Singh MK. Primary melanoma of the urethra: A rare neoplasm of the urinary tract. Int Urol Nephrol 2007; 39: 833-6.

Papeš D, Altarac S. Melanoma of female urethra. Med Oncol 2013; 30: 329.

Safadi A, Schwalb S, Ben-Shachar I, Katz R. Primary malignant urethral melanoma resembling a urethral caruncle. Urol Case Rep 2017; 15: 28-9.

El-Safadi S, Estel R, Mayser P, Muenstedt K. Primary malignant melanoma of the urethra: a systematic analysis of the current literature. Arch Gynecol Obstet 2014; 289: 935-43.

McComiskey M, Iavazzo C, Datta M, Slade R, Winter-Roach B, Lambe G, et al. Balloon cell urethral melanoma: differential diagnosis and management. Case Rep Obstet Gynecol 2015; 2015: 919584.

Cho ST, Song HC, Cho B, Choi WS, Lee WK, Lee YS, et al. Primary malignant melanoma of the female urethra. Korean J Urol 2012; 53: 206-8.