Baseline Hemoglobin Levels Predict AllCause Mortality After Saphenous Vein Graft  Interventions

Müjgan Tek; Mehmet Serkan Çetin; Berkten Berkalp; Basri Amasyalı; Mehmet Özgeyik; Savaş Çelebi; Erdem Diker

doi:10.5152/eurjther.2019.19050

Authors

Müjgan Tek Department of Cardiology, TOBB ETÜ Hospital, Ankara
Mehmet Serkan Çetin Department of Cardiology, TOBB ETÜ Hospital, Ankara
Berkten Berkalp Department of Cardiology, TOBB ETÜ Hospital, Ankara
Basri Amasyalı Department of Cardiology, TOBB ETÜ Hospital, Ankara
Mehmet Özgeyik Department of Cardiology, TOBB ETÜ Hospital, Ankara
Savaş Çelebi Department of Cardiology, TOBB ETÜ Hospital, Ankar
Erdem Diker Department of Cardiology, TOBB ETÜ Hospital, Ankara

DOI:

https://doi.org/10.5152/eurjther.2019.19050

Keywords:

All-Cause mortality, baseline hemoglobin, saphenous vein graft interventions

Abstract

Objective: Reduction in the baseline hemoglobin level is associated with poor outcomes in many cardiovascular conditions including percutaneous interventions of the native coronary arteries. However, this association has not been studied in patients with saphenous vein graft disease undergoing elective percutaneous intervention.
Methods: In this study, we evaluated the baseline hemoglobin levels of 105 patients undergoing saphenous vein graft intervention. The mean follow-up period was 42.4±18.4 months, and the outcome of our study was all-cause mortality.
Results: Twelve patients suffered all-cause mortality; the mean baseline hemoglobin levels of these patients were 2 g/dL lower (11.7±1.0 vs. 13.7±1.5, p=0.005) and their ejection fractions were 22% lower (49.3±10.8 vs. 38.3±12.4, p=0.014) than those of the patients without all-cause mortality. A hemoglobin cut-off value of 12.55 g/dL discriminated all-cause mortality with an accuracy of 85% (sensitivity: 83.3%, specificity: 76.4%, p≤0.001). Survival curve showed a survival benefit of 21 months for patients with hemoglobin levels higher than 12.55 g/dL (cumulative survival 95.3% vs. 70%, log rank p-value=0.001).
Conclusion: The baseline hemoglobin levels may be associated with all-cause mortality in patients undergoing elective saphenous vein graft interventions.

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