Knowledge of Dentistry Students about Local Anesthetic Systemic Toxicity and Intravenous Lipid Rescue Therapy: A Cross-Sectional Questionnaire-Based Study
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Keywords:
Dentistry, lipid emulsion, local anesthetic systemic toxicity, local anesthetics, toxicityAbstract
Objective: The aim of this study was to evaluate the level of consciousness of local anesthetic systemic toxicity (LAST) among dentistry students, which would provide helpful information for scheduling the educational content of future syllabus before graduation to prepare students for possible challenges in the future.
Methods: This study included 234 dentistry students, who were in the 3rd, 4th, and 5th degrees during the period 01 December 2018–01 April 2019, and was conducted using a cross-sectional, questionnaire-based design. The revised questionnaire form includes questions addressing the frequency of encountered LAST cases, signs of LAST they had seen, and treatments for LAST, particularly lipid treatment, they had used.
Results: The questionnaire was sent to 234 dentistry students in the 3rd, 4th, and 5th degrees at the Faculty of Dentistry, Gaziantep University, Gaziantep, Turkey, of whom 215 (91.88%) responded. The majority of participants (93%, n=200) declared that they received training about local anesthetics (LAs). Only one LA agent was preferred among 38.60% (n=83) of participants, whereas other participants preferred multiple agents. A significant majority of the participants (79.5%; n=171) declared that they did not observe LAST before this study, whereas only 15 (7%) students mentioned that they had encountered LAST but used an alternative therapy rather than intravenous lipid rescue therapy. None of the students personally applied lipid rescue therapy.
Conclusion: The results of this study implicate the evident need for additional educational effort to create awareness about LA use and effective management of LAST among dentistry students.
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References
Sagir A, Goyal R. An assessment of the awareness of local anesthetic systemic toxicity among multi-specialty postgraduate residents. J Anesth 2015; 29: 299-302.
Walsh AM, Moran B, Walsh SA. Knowledge of local anesthetic use among dermatologists. Dermatol Surg 2012; 38: 882-7.
Jensen-Gadegaard P, Skjønnemand M, Damgaard-Jensen J, Gottschau B. Limited knowledge of lipid rescue therapy in local anaesthetic systemic toxicity. Dan Med Bull 2011; 58: A4226.
Oksuz G, Urfalioglu A, Sekmen T, Akkececi N, Alpay N, Bilal B. Dentists knowledge of lipid treatment of local anaesthetic systemic toxicity. Niger J Clin Pract 2018; 21: 327-31.
Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979; 51: 285-7.
Di Gregorio G, Neal JM, Rosenquist RW, Weinberg GL. Clinical presentation of local anesthetic systemic toxicity: a review of published cases, 1979 to 2009. Reg Anesth Pain Med 2010; 35: 181-7.
Association of Anaesthetists of Great Britain and Ireland. Intralipid in the management of LA toxicity: guidance from the Association of Anaesthetists of Great Britain and Ireland (AAGBI), 2007. http://www.aagbi.org/publications/guidelines/docs/latoxicity07.pdf (accessed 26 Aug 2009).
Neal JM, Bernards CM, Butterworth JF 4th, Di Gregorio G, Drasner K, Hejtmanek MR, et al. ASRA practice advisory on local anesthetic systemic toxicity. Reg Anesth Pain Med 2010; 35: 152-61.
Rhee SH, Park SH, Ryoo SH, Karm MH. Lipid emulsion therapy of local anesthetic systemic toxicity due to dental anesthesia. J Dent Anesth Pain Med 2019; 19: 181-9.
Taghavi Zenouz A, Ebrahimi H, Mahdipour M, Pourshahidi S, Amini P, Vatankhah M. The incidence of intravascular needle entrance during inferior alveolar nerve block injection. J Dent Res Dent Clin Dent Prospects 2008; 2: 38-41.
El-Boghdadly K, Pawa A, Chin KJ. Local anesthetic systemic toxicity: current perspectives. Local Reg Anesth 2018; 11: 35-44.
Pinheiro AC, Marques JF, Vieira MS, Branco-De-Almeida LS. Dentists’ knowledge regarding signs and symptoms of the systemic toxicity of local anesthetic solutions. Rev Gaúch Odontol 2015; 41-6.
Donald MJ, Derbyshire S. Lignocaine toxicity; a complication of local anaesthesia administered in the community. Emerg Med J 2004; 21: 249-50.
Dorf E, Kuntz AF, Kelsey J, Holstege CP. Lidocaine-induced altered mental status and seizure after hematoma block. J Emerg Med 2006; 31: 251-3.
Marra DE, Yip D, Fincher EF, Moy RL. Systemic toxicity from topically applied lidocaine in conjunction with fractional photothermolysis. Arch Dermatol 2006; 142: 1024-6.
Ferguson W, Coogle C, Leppert J, Odom-Maryon T. Local anesthetic systemic toxicity (LAST): designing an educational effort for nurses that will last. J Perianesth Nurs 2019; 34: 180-7.
Urfalıoğlu A, Urfalıoğlu S, Oksuz G. The knowledge of eye physicians on local anesthetic toxicity and intravenous lipid treatment: questionnaire study. Turk J Ophthalmol 2017; 47: 320-5.
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