Is Blastocystis spp. Friendly?: A Current View of the Intestinal Microbiota


Abstract views: 100 / PDF downloads: 42

Authors

DOI:

https://doi.org/10.5152/EurJTher.2019.18086

Keywords:

Bacterial diversity, Blastocystis spp, dysbiosis, intestinal microbiota

Abstract

The intestinal microbiota has become the center of attention, not only in microbiology but also in all fields of medicine. There has been an intense activity in studies that investigate the composition and function of the intestinal microbiota. The imbalance in the diversity of bacteria that constitute microbiota has been defined as “dysbiosis” and associated with various diseases. Blastocystis spp. is a eukaryotic protist and the most prevalent protozoan of the human gastrointestinal system. The frequency of observed colonization of Blastocystis spp. in asymptomatic cases has made its association with diseases controversial. It was found in some studies that there is a positive correlation between Blastocystis and the bacterial diversity of the intestinal microbiota. This implies that the parasite may play a role in intestinal homeostasis. Human and animal studies on this subject play an important role in understanding this relationship.

Metrics

Metrics Loading ...

References

Kantor RS, Wrighton KC, Handley KM, Sharon I, Hug LA, Castelle CJ, et al. Small genomes and sparse metabolisms of sediment-associated bacteria from four candidate phyla. MBio 2013; 4: e00708-13.

Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R. Diversity, stability and resilience of the human gut microbiota. Nature 2012; 489: 220-30.]

Biedermann L, Rogler G. The intestinal microbiota: its role in health and disease. Eur J Pediatr 2015; 174: 151-67.

Arrieta MC, Stiemsma LT, Amenyogbe N, Brown EM, Finlay B. The intestinal microbiome in early life: health and disease. Front Immunol 2014; 5: 427.

Andersen LO, Stensvold CR. Blastocystis in Health and Disease: Are We Moving from a Clinical to a Public Health Perspective? J Clin Microbiol 2016; 54: 524-8.

Krogsgaard LR, Engsbro AL, Stensvold CR, Nielsen HV, Bytzer P. The prevalence of intestinal parasites is not greater among individuals with irritable bowel syndrome: a population-based case-control study. Clin Gastroenterol Hepatol 2015; 13: 507-13.

Scanlan PD, Stensvold CR, Rajilić-Stojanović M, Heilig HG, De Vos WM, O’Toole PW, et al. The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota. FEMS Microbiol Ecol 2014; 90: 326-30.

Petersen AM, Stensvold CR, Mirsepasi H, Engberg J, Friis-Møller A, Porsbo LJ, et al. Active ulcerative colitis associated with low prevalence of Blastocystis and Dientamoeba fragilis infection. Scand J Gastroenterol 2013; 48: 638-9.

Nourrisson C, Scanzi J, Pereira B, NkoudMongo C, Wawrzyniak I, Cian A, et al. Blastocystis is associated with decrease of fecal microbiota protective bacteria: comparative analysis between patients with irritable bowel syndrome and control subjects. PLoS One 2014; 9: e111868.

Andersen LO, Bonde I, Nielsen HB, Stensvold CR. A retrospective metagenomics approach to studying Blastocystis. FEMS Microbiol Ecol 2015; 91. pii: fiv072.

O’Brien Andersen L, Karim AB, Roager HM, Vigsnæs LK, Krogfelt KA, et al. Associations between common intestinal parasites and bacteria in humans as revealed by qPCR. Eur J Clin Microbiol Infect Dis 2016; 35: 1427-31.

Nagel R, Traub RJ, Allcock RJ, Kwan MM, Bielefeldt-Ohmann H. Comparison of faecal microbiota in Blastocystis-positive and Blastocystis-negative irritable bowel syndrome patients. Microbiome 2016; 4: 47.

Audebert C, Even G, Cian A; Blastocystis Investigation Group, Loywick A, Merlin S, Viscogliosi E, et al. Colonization with the enteric protozoa Blastocystis is associated with increased diversity of human gut bacterial microbiota. Sci Rep 2016; 6: 25255.

Yildiz S, Doğan İ, Doğruman-Al F, Nalbantoğlu U, Üstek D, Sarzhanov F, et al. Association of Enteric Protist Blastocystis spp. and Gut Microbiota with Hepatic Encephalopathy. J Gastrointestin Liver Dis 2016; 25: 489-97.

Forsell J, Bengtsson-Palme J, Angelin M, Johansson A, Evengård B, Granlund M. The relation between Blastocystis and the intestinal microbiota in Swedish travellers. BMC Microbiol 2017; 17: 231.

Simrén M, Barbara G, Flint HJ, Spiegel BM, Spiller RC, Vanner S, et al. Intestinal microbiota in functional bowel disorders: a Rome foundation report. Gut 2013; 62: 159-76.

Garcovich M, Zocco MA, Roccarina D, Ponziani FR, Gasbarrini A. Prevention and treatment of hepatic encephalopathy: focusing on gut microbiota. World J Gastroenterol 2012; 18: 6693-700.

Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, et al. Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon. PLoS Pathog 2012; 8: e1003000.

Lee SC, Tang MS, Lim YA, Choy SH, Kurtz ZD, Cox LM, et al. Helminth colonization is associated with increased diversity of the gut microbiota. PLoS Negl Trop Dis 2014; 8: e2880.

Lukeš J, Kuchta R, Scholz T, Pomajbíková K. (Self-) infections with parasites: re-interpretations for the present. Trends Parasitol 2014; 30: 377-85.

Downloads

Published

2023-04-01

How to Cite

Doğruman Al, F., Sarzhanov, F., & Erganiş, S. (2023). Is Blastocystis spp. Friendly?: A Current View of the Intestinal Microbiota. European Journal of Therapeutics, 25(4), 239–242. https://doi.org/10.5152/EurJTher.2019.18086

Issue

Section

Review Articles