Unexpected Falls in Schizophrenia: Clozapine-Induced Negative Myoclonus


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DOI:

https://doi.org/10.58600/eurjther2341

Keywords:

clozapine, myoclonus, schizophrenia

Abstract

Myoclonus, characterized by sudden involuntary muscle contractions, can occur in a variety of conditions, including as a side effect of clozapine, which is used in the treatment-resistant schizophrenia. This case study describes a 48-year-old female patient who developed negative myoclonus, manifested by knee flexion and falls, after starting clozapine. Despite dose reduction and the addition of valproic acid, symptoms persisted, highlighting the dose-dependent nature of clozapine-induced myoclonus and the need for clinicians to recognise this risk.

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References

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Published

2024-09-10

How to Cite

Karaağaç, M. (2024). Unexpected Falls in Schizophrenia: Clozapine-Induced Negative Myoclonus. European Journal of Therapeutics. https://doi.org/10.58600/eurjther2341

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