Cryptococcal Meningitis in a Human Immunodeficiency Virus Sero-positive Patient: A Case Study

Jayalakshami Srinivasan; Neha Singh; Nidhi Anam; Snehal Wagh; Shubhangi Sharma

doi:10.58600/eurjther1657

Authors

Jayalakshami Srinivasan Postgraduate Student, Department of Microbiology, MGM Medical College, Navi Mumbai, Maharashtra, India. https://orcid.org/0000-0002-0849-9892
Neha Singh Assistant Professor, Department of Microbiology, MGM Medical College, Navi Mumbai, Maharashtra, India. https://orcid.org/0009-0002-6658-008X
Nidhi Anam Postgraduate Student, Department of Medicine, MGM Medical College, Navi Mumbai, Maharashtra, India. https://orcid.org/0000-0003-2079-0217
Snehal Wagh Postgraduate Student, Department of Microbiology, MGM Medical College, Navi Mumbai, Maharashtra, India. https://orcid.org/0009-0006-3513-4852
Shubhangi Sharma Postgraduate Student, Department of Microbiology, MGM Medical College, Navi Mumbai, Maharashtra, India. https://orcid.org/0009-0006-5366-8778

DOI:

https://doi.org/10.58600/eurjther1657

Keywords:

cryptococcal meningitis, human immunodeficiency virus, cerebrospinal fluid, central nervous system, gram staining

Abstract

A 42-year-old female patient was admitted to the hospital with moderate-grade fever, severe headache, loss of appetite, and sore throat. She was suspected of Meningitis and her CSF sample was sent to the Laboratory for Microbiological Examination. The CSF sample obtained showed the presence of Capsulated budding yeast cells on India Ink Examination and Cryptococcus neoformans was isolated on SDA culture. The patient was recently diagnosed as HIV-Sero Positive and was immunocompromised leading to acquiring Cryptococcal meningitis. The lack of awareness of HIV-AIDS and delayed diagnosis of Cryptococcal meningitis led to a poor prognosis. Early diagnosis of HIV and timely treatment can improve the prognosis of the disease.

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