Use of Controlled Medications in the Emergency Department: Narcotics and Psychotropics


Abstract views: 32 / PDF downloads: 31

Authors

DOI:

https://doi.org/10.5152/eurjther.2020.19032

Keywords:

Benzodiazepine, emergency department, narcotic, opioid, psychotropic

Abstract

Objective: Although the trends and outcomes of controlled medications prescribed by emergency physicians especially opioids are well-defined in the literature, there is insufficient evidence regarding their parenteral use during emergency department (ED) visits. Thus, we aimed to determine the prevalence use of these drugs and the conditions under which they are ordered. Methods: We conducted a retrospective study from January to June 2018 at a secondary care ED in Turkey. Narcotics and psycho- tropics, were administered parenterally (intravenous or intramuscular) during patients’ ED visits. We obtained the following data from the registry and hospital records: time of use, age, sex, diagnosis, drug (active ingredient), and type of physician (general practitioner or attending). Results: During the six-month study period, parenteral controlled medication was used in 1111 ED visits (1% of all ED visits). Tramadol and pethidine were the most commonly used narcotic drugs in the ED. They were often used for musculoskeletal pain (29.1% and 47.1%, respectively) and abdominal pain (22.5% and 18.6%, respectively). ED revisits of patients who took these drugs were related to cancer pain. Meanwhile, diazepam and biperiden were the predominantly used psychotropics. Anxiety/agitation was diagnosed in 69.1% of patients who received diazepam and acute exacerbation of psychiatric diseases in 70.6% of patients who received biperiden. However, revisits of these patients to the ED were related to acute exacerbation of psychiatric diseases. Conclusion: The rate of controlled medication use in the studied hospital is much lower than that in developed countries. This finding can be attributed to different factors, such as physician attitude, patient demands, and possibly cultural differences. Finally, revisits of these patients to the ED were mostly related to acute exacerbation of chronic diseases.

Metrics

Metrics Loading ...

References

Von Kuenssberg Jehle D, Stiller G, Wagner D. Sensitivity in detecting free intraperitoneal fluid with the pelvic views of the FAST exam. Am J Emerg Med 2003; 21: 476-8.

Riddell J, Case A, Wopat R, Beckham S, Lucas M, McClung CD, et al. Sensitivity of Emergency Bedside Ultrasound to Detect Hydro- nephrosis in Patients with Computed Tomography-proven Stones. West J Emerg Med 2014; 15: 96-100.

Smith GD, Fry MM, Taylor D, Morgans A, Cantwell K. Effectiveness of the Valsalva Manoeuvre for reversion of supraventricular tachycar- dia. Cochrane Database Syst Rev 2015; 2: Cd009502.

Wen ZC, Chen SA, Tai CT, Chiang CE, Chiou CW, Chang MS. Electro- physiological mechanisms and determinants of vagal maneuvers for termination of paroxysmal supraventricular tachycardia. Circu- lation 1998; 98: 2716-23.

Quigley AJ, Stafrace S. Ultrasound assessment of acute appendicitis in paediatric patients: methodology and pictorial overview of find- ings seen. Insights Imaging 2013; 4: 741-51.

Mazer-Amirshahi M, Mullins PM, Rasooly I, van den Anker J, Pines JM. Rising opioid prescribing in adult U.S. emergency department visits: 2001-2010. Acad Emerg Med 2014; 21: 236-43.

Barnett ML, Olenski AR, Jena AB. Opioid-Prescribing Patterns of Emergency Physicians and Risk of Long-Term Use. N Engl J Med 2017; 376: 663-73.

Demircan D, Gulmez SE, Donertas B, Topcu I, Yilmaz H, Berkman K, et al. Use of drugs subject to controlled prescriptions: a retrospective analysis. Balkan Med J 2013; 30: 46-53.

Öztürk O, Öztürk G. Retrospective Analysis of Green Coloured Pre- scriptions Isuued in A Family Medicine Unit. Turkish Journal of Fam- ily Medicine and Primary Care 2017; 11: 38-42.

Fortuna RJ, Robbins BW, Caiola E, Joynt M, Halterman JS. Prescribing of controlled medications to adolescents and young adults in the United States. Pediatrics 2010; 126: 1108-16.

McAllister MW, Aaronson P, Spillane J, Schreiber M, Baroso G, Krae- mer D, et al. Impact of prescription drug-monitoring program on controlled substance prescribing in the ED. Am J Emerg Med 2015; 33: 781-5.

Sutter ME, Wintemute GJ, Clarke SO, Roche BM, Chenoweth JA, Gutier- rez R, et al. The Changing Use of Intravenous Opioids in an Emergency Department. West J Emerg Med 2015; 16: 1079-83.

Patanwala AE, Keim SM, Erstad BL. Intravenous opioids for severe acute pain in the emergency department. Ann Pharmacother 2010; 44: 1800-9.

Han X, Ouyang H, Chen X, Huang Y, Song Y, Zhang M, et al. Aberrant expression of Igf2/H19 in porcine parthenogenetic fetuses and pla- centas. Anim Reprod Sci 2013; 139: 101-8.

Hoppe JA, Nelson LS, Perrone J, Weiner SG, Prescribing Opioids Safely in the Emergency Department Study I, Prescribing Opioids Safely in the Emergency Department PSI. Opioid Prescribing in a Cross Section of US Emergency Departments. Ann Emerg Med 2015; 66: 253-9.e1.

O’Connor AB, Zwemer FL, Hays DP, Feng C. Outcomes After Intrave- nous Opioids in Emergency Patients: A Prospective Cohort Analysis. Acad Emerg Med 2009; 16: 477-87.

Patel PM, Goodman LF, Knepel SA, Miller CC, Azimi A, Phillips G, et al. Evaluation of Emergency Department Management of Opioid-Tol- erant Cancer Patients With Acute Pain. J Pain Symptom Manage 2017; 54: 501-7.

Ernst FR, Mills JR, Berner T, House J, Herndon C. Opioid Medica- tion Practices Observed in Chronic Pain Patients Presenting for All-Causes to Emergency Departments: Prevalence and Impact on Health Care Outcomes. J Manag Care Spec Pharm 2015; 21: 925-36.

Paulozzi LJ, Strickler GK, Kreiner PW, Koris CM, Centers for Disease C, Prevention. Controlled Substance Prescribing Patterns--Prescription Behavior Surveillance System, Eight States, 2013. MMWR Surveill Summ 2015; 64: 1-14.

Schmitz A. Benzodiazepine use, misuse, and abuse: A review. Ment Health Clin 2016; 6: 120-6.

Kapil V, Green JL, Lait CL, Wood DM, Dargan PI. Misuse of benzodi- azepines and Z-drugs in the UK. Br J Psychiatry 2018; 205: 407-8.

Kaufmann CN, Spira AP, Alexander GC, Rutkow L, Mojtabai R. Trends in prescribing of sedative-hypnotic medications in the USA: 1993- 2010. Pharmacoepidemiol Drug Saf 2016; 25: 637-45.

Downloads

Published

2023-05-16

How to Cite

Aslaner, M. A., & Baykan, N. (2023). Use of Controlled Medications in the Emergency Department: Narcotics and Psychotropics. European Journal of Therapeutics, 26(3), 160–164. https://doi.org/10.5152/eurjther.2020.19032

Issue

Section

Original Articles