Activity Investigation of Combination of Sulbactam with Ampicilline and  Cefoperasone on Listeria

Muzaffer GÖZ; A.Tevfik CENGİZ

doi:10.58600/eurjther.1995-6-1-1556-arch

Authors

Muzaffer GÖZ Ankara Üniversitesi Tıp Fakültesi Mikrobiyoloji ABD. Dr.
A.Tevfik CENGİZ Ankara Üniversitesi Tıp Fakültesi Mikrobiyoloji ABD.Prof.Dr.

DOI:

https://doi.org/10.58600/eurjther.1995-6-1-1556-arch

Keywords:

Listeriosis, Listeria monocytogenes

Abstract

In this study, in vitro activity of the combination of sulbactam+ampicilline and cefoperasone, sulbactam +ampicilline and sulbactam +cefoperasone with ampicilline and cefoperasone were investigated against 111 Listeria strains isolated from different dinical and other samples, by disc diffusion method.

Listeria strains that was used in this study, was sensitive to 24.3 % ampicilline and the combination of sulbactam+ampicilJine 59.5 %. At the same time Listeria strains was sensitive to 36.04 % cefoperasone and 69.4 % sulbactam +cefoperasone.

It was observed that, the combination of ampicilline+sulbactam with respect to ampicilline was 2.45 times and sulbactam+cefoperasone combination respect cefoperasone was 1.925 times more effective.

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References

- Abadie SM, Dalovisio RJ, Pankey GA, Gortez LM:Listeria monocytogenes arthritis in a renal transplant recipient. J Infect Dis 156:413, 1987.

- Anğ Ö, Ergenç H, Çetin ET, Töreci K:Listeria monocytogenes'in etken olduğu bir menenjit vakası. 15.Türk Mikrobiyoloji Kongresi'nde, 1972, 387-392.

- Bassan R:Bacterial endocarditis produced by Listeria monocytogene. Am J Clin Pathol 63:522, 1975.

- Gellin BG, Broome CV:Listeriosis., JAMA, 261:1313-1320, 1989.

- Gordon S, Singer C:Listeria monocytogenes cholecytitis. J Infect Dis 154:918, 1986.

- Isiadinso OA:Listeria sepsis and meningitis:A complication of renal transplantation. JAMA 243:842, 1975.

- Albritton WL, Cochi SL, Feeley JC:Overview of neonatal listeriosis. Oin Invest Med 7:311, 1984.

- Barresi AJ:Listeria monocytogenes:A cause of premature labor and neonatal sepsis. Am J Obstet Gynecol 136:410, 1980.

- Azimi PH, Koranyi K, Lindsey KD:Listeria monocytogenes. Synergistic effects of ampicillin and gentamicin. Am J Clin Pathol 72:974-1979.

- Cengiz AT, Göz M:Listeria Suşlarının Çeşitli Antibiyotiklere Duyarlılıklarının Araştırılması, İnfeksiyon Dergisi(Turkish Journal of Infection) 5(2):93-95, 1991.

- Coşar G, Tümbay E, İnci R:Susceptibility of Listeria monocytogenes to ampicillin and ampicillin-sulbactam combination-an in vitro study with diffuson test. Infeks Derg 2:599, 1988.

- Boissivon A:Action bacteriostatique et bactericide comparee des Penicilines Cephalosporines, Aminosides et des associations Ampicilline-Gentamicine et Triethoprime-sulfamethoxazole sur Listeria monocytogenes. Ann Microbiol(Inst.Pasteur) 131 B:267, 1980.

- Larsson S, Wa)der MH, Cronberg SN, Forsgren AB:Antimicrobial susceptibilities of Listeria monocytogenes strains isolated from 1958 to 1982 in Sweden. Antimicrob Agents Chemother 28:12, 1985.

- Monograf:Sulperazon, Pfizer İlaçlan A.Ş. 1992.

- National Committee for Oinical Laboratory Standards:Performance Standards for Antimicrobic Disc Susceptibility Tests, 3 rd Edition. Approved Standards:M2-A3 NCO.S, Villanova, PA, 1984.

- Krause W, Embre JE, Mac Donald SW, Acker WC, Embil JA:Congenital listeriosis causing early neonatal death. CMAJ 127:36, 1982.

- Armstrong D:Listeria monocytogenes. Principles and Practice of Infectious Diseases, 3rd Edition(Ed:Mandell GL, Douglas RG, Bennet JE)'de. New York, Churchill-Livingstone I.nc, 1990, 1587-1593.

- Hof H, Waldenmaler G:Therapy of experimental listeriosis-An evaluation of different antibotics. Infect 16(Suppl 2):171, 1988.

- Reynaud A, Espanze EP, Papin S, Courtieu AL:Etude de la sensibilite aux antibiotiques de 139 souches de Listeria serotypees par le Centre National de Reference en 1983. Ann Microbiol(Inst.Pasteur)135 B:331, 1984.

- Moellering RC; Medoff G,leech I, Wennersten C, Kunz LC:Antibiotic synergism against Listeria monocltogenes. ;Antimicroö· Agents Chemother 1:30, 1972.