The ldentity and Antibiotic Sensitivities of Microorganisms lsolated From Throat, Nose, Urine, Fecal and Blood Cultures of Patients with Hematological Malignancies


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Authors

  • Ramazan ULUHAN Çukurova Univ. Tıp Fak. Mikrobiyoloji ABD. Uz.Dr.
  • Akgün YAMAN Çukurova Üniv.Tıp Fak.Mikrobiyoloji ABD. Yrd. Doç. Dr.
  • Erol AKAN Çukurova Üniv. Tıp Fak. Mikrobiyoloji ABD.Prof.Dr.

DOI:

https://doi.org/10.58600/eurjther.1995-6-2-1531-arch

Keywords:

Malignancy, Microorganism, Antibiotic susceptibility

Abstract

In order to determine the possible etiologic agents and their antibiotic sensitivities frorn patients with hernatologic malignancies, throat, nose, urine, fecal and blood specimens from 98 rnale and 38 female patients were evaluated microbiologically. Out of a total of 612 culture specirnens, the probable pathogens which were isolated, included 188 (30.72%) Gram positives and 66(10.78 %) Gram negatives. Bacteria which might have been possible cause of infection were not isolated from 358 specimens. The Gram positive bacterium most frequently isolated was S.aureus(39.8 %) the most effective antibiotic was amikacin (71 %) and the least effective was penicillin (34 %). Out of the Gram negative bacteria, E.coli was most frequently isolated and the most effective antibiotics were aztreonam (72 %), amikacin (71 %) and ofloxacin (71 %). The least effective were chloramphenicol (17 %) and amoxycillin (32 %).

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References

- SchimptT SC:Iııfections in !he compromised host.Iıı Mandell GS, Douglas RG, Bennett JE:Principles and Practice oflııfectious Diseases. New York, John Wiley and Sons, 22S8-66, 1990.

- Schimpff SC:Iııfections in patients with cancer. Moossa AR, Robson MC, SchimptT SC.Comprchensive Textbook ofüncology, Wavcrly Press-Baltimore, 367-77, 1986.

- Wade JC, SchimptTSC, Newman KA,et al:Staphylococcus epidemıidis:An increasing cause of iııfection in patients with granulocylopcnia. Ann Iııt. Med. 97: 503-8, l 982

- Hathom JW:Empiricııt antibioticıı for fcbrile neutropcnie cıınccr patientıı. Eur J Cancer Clin Oncol. 2S:43-51, 1989 . .

- Pizzo PA:Evalıuıtiou of fovor in lbo pationt witlı cıuıccr. Eıır J Cıuıccr Clin Oncol 25:9-16, 1989.

- Pizz.o PA, Ladish SL, Robichaud K:Treatment of gram-positive septicemia in cancer patients. Cancer 45:206-7, 1980.

- Friedman LE, Brown AE, Miller DR, et al:Staphylococcus epidemıidis septicemia in children with leukemia and ymphoma AJDC. 138:715-20, 1984.

- Heruy SA:Chemoprophylaxis of bacterial infections in granulocytopenic. Am J Med 76:645- SO, 1984.

- Karp JE, Merz WG, Hendricksen C, et al:Oral norfloxacin for prevention of gram-negative bacterial infections in patients with acuie leukemia and granulocytopenia. Ann Int Med 106: 1- 7, 1987.

-Rubin M, Hatlıom JW, Marshall D, et al:Gram-positive infection and use of vancomycin in 550 cpisodcs of fever and neutropenia. Ann lııt Mcd 108:30-5, 1988.

- Salman N:İmmün yetmezliklerde görtılen infeksiyon ve tedavileri, Çalangu S, Eraksoy H, Özsut H. lnteksiyon Hastalı.klan. "90-91", 107-18, Yüce Yayınlan, İstanbul, 1990. 12- Sotman SB, Sclıımpff SC, Young VM:Staphylococcus bacteremia in patient with acute leukemia. Anı J Med 69:814-18, 1980.

-Meyers JD, McGuffın RW, Neiman PE, et al:Toxicity and efficacy of human leukocyte interferon for treatrnent of cytomegalovirus pneumonia after marrow transplantation. J Infect Dis 141:555-62, 1980.

- Winston DJ, Dudnick DV, Chapin M, et al:Coagulase-negative Staphylococcal bacteremia in patients receiving immunosuppressive therapy., Arch Intern Med 143:32-36, 1983.

-Myers JP, Linneman CC Jr:Bacteremia due to methicillin resistant Staphylococcus aureus. J Infect Dis 145:532-36, 1982.

-Fainstain V, Rodriguez V, Turk M, et al:Patterns of oropharyngeal and fecal flora in patients with leukemia. JİnfectDis 144:10-18, 1981.

-Brown AE:Neutropenia, Fever and infection. Anı J Med 76:421-29, 1984.

- Grob J, Francıolı P, Pecoud A, et al:Low morbidity and mortality infection in neutropenic patients, a possible result of multiple measures of infection prevention. Schweiz Med Wschr. 113(14):70-75, 1983.

-Feld R, Bodey GP:Infections in patients with Malignant Lymphoma Treated With Combination Chemotherapy. Cancer. 39:1018-25, 1977.

- Jones PG, Rolston KVl, Fainstein V, et al:Aztreonam therapy in neutropenic patients with cancer. Anı J Med 81: 24 3-48, 1986.

-Akalın E:Birinci Ulusal Enfeksiyon Hastalıklan Kongre Kitabı. 259-60, İzmir, 1987.

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Published

1995-06-01

How to Cite

ULUHAN, R., YAMAN, A., & AKAN, E. (1995). The ldentity and Antibiotic Sensitivities of Microorganisms lsolated From Throat, Nose, Urine, Fecal and Blood Cultures of Patients with Hematological Malignancies. European Journal of Therapeutics, 6(2), 180–187. https://doi.org/10.58600/eurjther.1995-6-2-1531-arch

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