The Effect of Truncal Vagatomy And Two Different Pyloroplasty Procedures on Gastric Emptying

Avni Gökalp; Zeki Çelen

doi:10.58600/eurjther.1999-10-1-2-1503-arch

Authors

Avni Gökalp Gaziantep Üniversitesi Tıp Fakültesi Genel Cerrahi Anabillim Dalı, Gaziantep
Zeki Çelen Gaziantep Üniversitesi Tıp Fakültesi Nükleer Tıp Anabilim Dalı, Gaziantep

DOI:

https://doi.org/10.58600/eurjther.1999-10-1-2-1503-arch

Keywords:

Gastric emptying, radionuclid studies, pyloroplasty

Abstract

Solid and liquid radionuclid gastric emptying studies were conducted in 40 male Sprague-Dawley rats. in ten animals, bilateral truncal vagotomy+ Heineke Mikulicz pyloroplasty was performed and in ten animals bilateral truncal vagotomy+ Cassimally pyloroplasty was carried out. Twenty animals acted as controls in whom ten were unoperated group and in ten only a laparotomy was performed. Gastric emtying was measured weekly in first 4 week and monthly tor 4 months both in experiment and control groups. Gastric emptying was unchanged in unoperated controls. Animals in which a laparatomy was performed had delayed solid and liquid emptying tor the first 4 weeks after operation (p<0.05). Following Heineke- Mikuklicz pyloroplasty, liquid emptying was accelerated tor 16 weeks (p<0.05). Solid ernptying was delayed tor 16 weeks. Animals subjected to Cassimally pyloroplasty, similar to tormer group, showed an acceleration in liquid emptying tor 16 weeks. Significant gastric retention of solids also occured tor 16 weeks in this group (p<0.05).

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