Prevalence of Hepatitis B in Gaziantep Province,Turkey: A Hospital-Based Serosurvey of 2045 Children

Ziya Bayraktaroğlu; Yavuz Coşkun; Murat Karaoğlan; Ercan Sivaslı

doi:10.58600/eurjther.1999-10-1-2-1485-arch

Authors

Ziya Bayraktaroğlu Department of Pediatrics, University of Gaziantep Faculty of Medicine, Gaziantep, Turkey
Yavuz Coşkun Department of Pediatrics, University of Gaziantep Faculty of Medicine, Gaziantep, Turkey
Murat Karaoğlan Department of Pediatrics, University of Gaziantep Faculty of Medicine, Gaziantep, Turkey
Ercan Sivaslı Department of Pediatrics, University of Gaziantep Faculty of Medicine, Gaziantep, Turkey

DOI:

https://doi.org/10.58600/eurjther.1999-10-1-2-1485-arch

Keywords:

seroepidemiolgy, hepatitis B virus, HBsAg

Abstract

A hospital-based serosurvey of !he prevalence of hepatitis B virus (HBV) was conducted in Gaziantep province, Turkey. Two thousand and forty-five children were tested for HBV markers with commercial enzyme-linked immunosorbent assay kils. One-hundred and fifty-one of the 2045 children (7.3%) were found to be positive for HBsAg, 373 (18.2%) to anti-HBs. Significant differences were seen between the prevalence of HBsAg in males (4.5%) and females (2.8%). HBsAg and anti-HBs seropositivity were increased with the age in both sex. Among the 567 household members of 151 HBsAg positive children, prevalence of HBsAg and anti-HBs were 19% and 34.9% respectively. Perinatal transmission of HBV infection, high prevalence in preadolescent/ adolescent group and familial clustering of the infection should be laken into account for the dynamics of HBV infection in !his part of Turkey.

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