Altered platellet volume in patients with diabetes mellitus Type II

Abstract

There are changes in platelet functions during the course of various diseases. Platelet volume is one of the indicators of platelet functions.160 type II Diabetes Mellitus patients (62 men, 98 women) who are followed by Gaziantep University Medical Faculty lnternal Medicine were laken to the study as patient group. Far the control group 60 people (17 men, 43 women) were taken to the study who had similar ages with the patient group. Mean age of the patient group was 53,40± 11,67 years. Far the control group it was 51,98±9,24 years. Mean duration of the diabetes in the study group was 101.11 ±80.85 months. Mean HbA1c levels was 9.03±2,00. Mean platelet numbers of the study group was 273,394±99,254x106 /L. Far the control group it was 6 250,233± 102.469x1 O /L and there was no significiant difference between them (1=10,09 p>0,05). Mean platelet volume of the study group was 8,55± 1.58 fl and 7 .30± 1.32 fl tor the control group. There was statistically significiant difference between (t=2,99,p<0,05). in the study group, there was no significiant difference among the correlations of platelet volumes, platelet numbers, duration of diabetes and HbA1c levels. As a result platelet functions were altered in diabetic patients and this was possibly related with the accelerated atherosclerosis in diabetes mellitus.