The Comparison of Midazolam and Ketamine as an Oral Premedication in Paediatric Anaesthesia

Sıtkı GÖKSU; Ünsal ÖNER; Nursan TAHTACI; Demet GÖĞÜŞ; Gülen AYDENİZ

doi:10.58600/eurjther.1996-7-1-2-1448-arch

Authors

Sıtkı GÖKSU Gaziantep Üniversitesi Tıp Fak. Anesteziyoloji ve Reanimasyon Anabilim Dalı
Ünsal ÖNER Gaziantep Üniversitesi Tıp Fak. Anesteziyoloji ve Reanimasyon Anabilim Dalı
Nursan TAHTACI Gaziantep Üniversitesi Tıp Fak. Anesteziyoloji ve Reanimasyon Anabilim Dalı
Demet GÖĞÜŞ Gaziantep Üniversitesi Tıp Fak. Anesteziyoloji ve Reanimasyon Anabilim Dalı
Gülen AYDENİZ Gaziantep Üniversitesi Tıp Fak. Anesteziyoloji ve Reanimasyon Anabilim Dalı

DOI:

https://doi.org/10.58600/eurjther.1996-7-1-2-1448-arch

Keywords:

Premedication, midazolam, ketamine, sedation

Abstract

ln this study the effectiveness of midazolam and ketamine in oral preinedication were investigated in paediatric cases that would have tonsillectomy operation. The patients were divided in two groups; ASA 1-11 that included fourty cases aged 1 year to 10 years. Twenty minutes before general anaesthesia midazolam (0.5 mg/kg) mixed with cherry juice was given to the first group and ketamine (6 mglkg) in the same mixture to the second group peroral. The sedation degree was evaluated by ChiSquare test according to Wilton 's Sedation Scala. ln addition the patients reaction to the face mask and the adverse effects of the drugs were assessed. There is no signifıcance between the two groups (p>0.05). The reaction to the face mask application was observed in 3 cases of midazolam group and 2 cases of ketamine group. As adverse effects in midazolam group; diplopia in 1 case, secreation increase in 2 cases and in ketamine group nistagmus in 4 cases, tongue fasciculation in 2 cases and oral secreation increase in 7 cases were observed.

As a result we suggest that due to the easy usability, good sedation effect and causing no respiratory depression, oral midazolam may be used as an alternative agent to ketamine in premedication.

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