Evaluation of Cardiovascular Autonomic Neuropathy in Niddm with Radionuclide Ventriculography

Abstract

The aim of our study is to observe the relation between cardiovascular autonomic neuropathy (CON) in noninsulin dependent diabetes mellitus (NlDDM) and the left ventricle functions. We have three groups in this study. ln the first group of 30 patients with anamnestic diabetic ages between 0-1O years. The second group, 30 patients whose diabetes ages are older than 1O years. ln the control group there are 20 healty peoples. CON tests was performed in every patient. The left ventricle functions were observed by radionuclid ventriculography (RNV). When CON ratio in the diabetes mellitus (DM) groups is compared with, the control group significant difference was found between them (p<0.05). When the DM groups are compared among themselves, it was realised that there is a statistically significant difference (p<0.01). ln the DM during the time increased the frequency and severity of CON increased also. When the systolic function of the left ventricle was compared among themselves and with the control group, no statistical significant difference was observed (p<0.05). lt's concluded that DM doesn't effect systolic function of the left ventricle. Significant dif.ference is fouııd between the DM groups and the control group (p<0.01 ). It's found that DM effect diastolic fuııctioıı of the left ventricle in the early period diastolic disfunction emerges. Besides, in the %85 of the patients with the diastolic disfunction CON is found. Lastly it is concluded that as the severity of CON increases, the possibility ta observe the frequency of diastolic disfunction alsa increases.