Beta-Lactamase Activity and the Resistance of Ampicillin in Salmonella Species

Hüseyin GÜN; Mehmet BAYSALLAR; Ayten KÜÇÜKKARAASLAN; Ahmet BAŞUSTAOĞLU; Ali ALBAY

doi:10.58600/eurjther.1994-5-1-1413-arch

Authors

Hüseyin GÜN GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD.Bşk.Doç.Dr.
Mehmet BAYSALLAR GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD.Yrd.Doç.Dr.
Ayten KÜÇÜKKARAASLAN GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD.Doktora öğrencisi
Ahmet BAŞUSTAOĞLU GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD.Yrd.Doç.Dr.
Ali ALBAY GATA Mikrobiyoloji ve Klinik Mikrobiyoloji ABD.Doktora öğrencisi

DOI:

https://doi.org/10.58600/eurjther.1994-5-1-1413-arch

Keywords:

Salmonella, Beta-lalctamaz, Ampicillin

Abstract

Resistance to chloramphenicol and ampicillin, first choice drugs in the treatment of salmonellosis, has been increasing day to day. This resistance generally depends on plasmid mediated beta-lactamase activity.

The ease of plasmid tranfering plays an important role in the spread of antibiotic resistance from one bacterial strain to another.

In this study, beta-lactamase activity and the resistance of ampicillin in totally 97 salmonella strains isolated from stool and blood specimens were investigated. Beta-Jactamase activity was detected in 38 of these bacteria. Except for a beta-lactamase positive strain of S.schottmuelleri, the resistance of ampicillin was detected in all salmonella strains having beta-lactamase enzyme.

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