A Case Report of Maternal Diabetes and Fetal Caudal Regression Syndrome
Abstract views: 58 / PDF downloads: 72
DOI:
https://doi.org/10.58600/eurjther.2007-13-2-1379-archKeywords:
Caudal regression syndrome, Prenatal diagnosis, Maternal diabetesAbstract
A 28 old years women patients with 16 weeks pregnant and tip 1 insulin dependent diabetes mellitus referred to our department for her routin control. On her obstetric ultranography a single, viable, appropriate with 16 weeks fetus was seen.The fetal spine was sudden cut at lumbosacral vertebrae level and low limbs were shorter. After termination of her pregnancy, the baby's pelvic anteroposterior and lateral X-Ray of the lower segment showed absence of all sacral and distal lumbar vertebrae, resulting in fusion of iliac bones in the midline.
Metrics
References
Singh SK, Singh RD, Sharma A. Caudal Regression Syndrome-case report and review of literature. Pediatr Surg Int 2005:383;1451-4.
Zaw W, Stone DG. Caudal regression syndrome in twin pregnancy with type 2 diabetes. J Perinatol 2002;22:171- 174.
Pang D. Sacral agenesis and caudal spinal cord malformation. Neurosurgery 1993;32:755-778.
Jaffe R, Zeituni M, Fejgin M. Caudal Regression Syndrome. Fetus Spinal Anomalies 1991;7561:1-3.
Versiani BR, Gilbert-Barness E, Giuliani LR, Peres LC. Caudal dysplasia sequence: severe phenotype presenting in offspring of patients with gestational and pregestational diabetes. Clin Dysmorphol 2004;13:1-5.
Adam PA, Teramo K, Raiha N. Human fetal insülin metabolism early in gestation. Response to acute elevation of the fetal glucose concentration and placental transfer of human insulin I-131. Diabetes 1969;18:409-16.
Steinke J, Driscoll SG. The extractable insulin content of pancreas from fetuses and infants of diabetic and control mothers. Diabetes 1965;14:573-8.
Miller E, Hare JW, Cloherty JP. Elevated maternal hemoglobin A1c in early pregnancy and major congenital anomalies in infants of diabetic mothers. N Engl J Med 1981;304:1331-4.
Valenzano M, Paoletti R, Rossi A. Sirenomelia pathological features, antenatal ultrasonographic clues, and a review of current embryogenic theories. Human Reprod Update 1999;5:82-86.
Halil A, Halil Y, Nurkul C, Gökhan Y.Prenatal diagnosis of caudal regression syndrome- case report. BMC Pregnancy Childbirth 2001;1:8.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 European Journal of Therapeutics
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.