Central Precocious Puberty in a 14-Month-Old Infant Girl With Vaginal Bleeding
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DOI:
https://doi.org/10.58600/eurjther.2010-16-2-1281-archKeywords:
Central precocious pubery, Vaginal bleeding, Idiopathic, LeuprorelinAbstract
Precocious puberty is defined as the onset of secondary sexual characteristics before 8 year of age in girls. The first sign is generally development of the breast related with early activation of hypothalamic- pituitary-gonadal axis. Although central precocious puberty is mostly idiopathic the cause may be hypothalamic tumor, malformation, hydrocephalus and radiotheraphy. GnRH stimulation test is gold standard for diagnosis. GnRH agonists especially leuprorelin is very effective for treatment of idiopathic central precocious puberty. This case is presented because of vaginal bleeding is unusual cause of administration for this age.
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