Small cell carcinoma of the prostate in differential diagnosis - A case report: Ayırıcı tanıda prostatın küçük hücreli karsinomu: Olgu sunumu

Münire Durmaz; Fahriye Kılınç; İbrahim Buldu; Halil Kıyıcı; Bilal Arık

doi:10.5152/EurJTher.2016.010

Authors

Münire Durmaz Department of Pathology, Faculty of Medicine, Mevlana University, Konya
Fahriye Kılınç Department of Pathology, Faculty of Medicine, Mevlana University, Konya
İbrahim Buldu Department of Urology, Faculty of Medicine, Mevlana University, Konya
Halil Kıyıcı Department of Pathology, Faculty of Medicine, Mevlana University, Konya
Bilal Arık Department of Radiology, Faculty of Medicine, Mevlana University, Konya

DOI:

https://doi.org/10.5152/EurJTher.2016.010

Keywords:

Extrapulmonary, small cell carcinoma, prostate

Abstract

Extrapulmonary small cell carcinomas are rare, aggressive malignant neoplasms with frequent metastases. These tumors mainly occur in the upper respiratory tract, esophagus and urogenital system. Small cell carcinomas of the prostate constitute less than 1% percentage of all prostate cancers. They can also develop in patients with previously diagnosed prostatic adenocarcinoma and treated with androgen deprivation therapy. It is important to detect neuroendocrine differentiation and distinguish pure small cell carcinoma from poorly differentiated acinar adenocarcinoma. In this article, a case of prostatic small cell carcinoma that applied to androgen deprivation therapy because of a former diagnosis of prostatic adenocarcinoma three years ago, is presented with associated differential diagnosis, major histopathologic and immunohistochemical features, treatment and the prognosis and literature knowledge.

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