The Results of the Therapies with Different Drug Combinations in 120 Brucellosis Cases.
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https://doi.org/10.58600/eurjther.19920301-1196Keywords:
Brucellosis, Treatment of BrucellosisAbstract
Son iki yıl içinde akut bruselloz tanısı konulan 120 olgu 45 gün süreyle tedaviye alındı. Hastalar 4 farklı antibiyotik kombinasyonu ile tedavi edildi. Birinci gruba ofloxacin (800rng/gün), ikinci gruba Streptomycin (1 gr/gün:) + Tetracyclin (2 gr/gün), üçüncü gruba Rifampin (900 mg/gün) + Doxycycline (200 mg/gün) + Trimethoprim-Sulfarnethoxazole (320-1600 mg/gün), dördüncü gruba ise Rifarnpin (900 mg/gün) + Doxycycline (200 mg/gün) tedavi şemaları uygulandı. Streptomycin 15 gün süreyle hergün, daha sonra haftada iki gün 1 gr/gün dozunda verildi. Diğer tedavi rejimleri hergün verilerek 45 gün süreyle uygulandı. Yapılan karşılaştırmalı çalışmada en fazla nüks oranı Streptomycin + Tetracycline kombinasyonunda görüldü.
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