Glycosylated Hemoglobin (HbA1c) in Chronic Renal Failure

Hanife Uygur; Yalçın Kepekçi

doi:10.58600/eurjther.19920301-1186

Authors

Hanife Uygur Çukurova Üniversitesi Tıp Fakültesi Biyokimya Birimi Uz.Dr.
Yalçın Kepekçi Gaziantep Üniversitesi Tıp Fakültesi İç Hast.ABD.Yrd.Doç.Dr.

DOI:

https://doi.org/10.58600/eurjther.19920301-1186

Keywords:

Chronic renal failure, glycosylated hemoglobin

Abstract

Glycosylated Hemoglobin (HbAıc) in Chronic Renal Failure Glycosylated hemoglobin levels were investigated in chronic renal failure patients who are compansated or on regular hemodialysis program, and in a group of healthy volunteers. The blood urea nitrogen (BUN) and serum creatinin levels were also determined. Patients who are on hemodialysis (Group lli) had decreased levels of HbAıc compared to patikents on patients with compansated chronic renal failure (group II) (17.0 ± 4.4 % to 16.3 ± 0.8 %). No correlation was found between HbAıc values, serum creatinin and BUN levels. The results were discussed considering various factors may affect on the level of glycosylated hemoglobin.

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References

- Hemoglobin A and diabetes A reappraisaL Brit Med J 281:1304,1980.

- Jovanovic L and Peterson CM.: The clinical utility of glycosylated hemoglobin. Am J Med 70:331, 1981.

- Panzer 5., Kronik G., Lechner K., et al: Glycosylated hemoglobins (HbG): An index of red cell survival. Blood, 59:1348, 1982.

- Casparie AF., Miedema K.: Glycosylated hemoglobin in diabetes and renal failure. Lancet, ii:758, 1977.

- Dandona P., Freedman D., Moorhead JF.:Glycosylated hemoglobin in chronic renal failure. BMJ 2:1183, 1979.

- Fluckiger R., Harmon W., Meier W., et al: Hemoglobin carbamyletion in uremia. N Eng J Med 304; 823-27, 1981.

- Gabbay Kh., Hasty K., Breslow JL., et al: Glycosylated heırtoglobins and long-termi blood glucose control in diabetes mellitus.J Oin Endocrinol Metab. 44:859-64, 1977.

- Reagent Data Handbook for the Technicon SMA 12/60 System; Technicon alnastruments corporatikon New York, 1973. 9

- Stanson GK., Davis R and Richmond J.: Glycosylated haemoglobin-A in renal failure. lancet i, 100, 1978.

- De Boer MJ., Miedema K., Casparie AF.: Glycosylated hemoglobin in renal failure. Diabetologie 18; 437-40, 1980.

- Hanson U., Hagenfelt L., Hagenfeld K.: Glycosylated hemoglobins in normal pregnancy: Sequential Changes and relation to birth weight. Obstet Gynecol, 62: 741043, 1983.

- Bruns ED and Wills RM.: Glycosylation and uremia. Lancet ii, 344, 1984.

- D'Haese PC., et al: Contrubution of paranteral and dialysate solutions to the aluminium accumulation in dialysis patients (letter) Blood Purif 8 (6):359-62, 1990.

- Thieler H., et al: Fatal lead poisonings at a DDR dialysis center (Letter) Dtsch Med Wochenschr Apr 26, 116 (17): 678, 1991 (Ger).

- Akanji AO., et al: Effect of acetate on blood metabolites and glucose tolerance during hemodialysis in uraemic non diabetic and diabetic subjects Nephron 57(2):137-43, 1991.