Phosphodiesterase Inhibitors and Using in the Treatment of Congestive Heart Failure: [FOSFODİESTERAZ İNHİBITÖRLERİ VE KONJESTİF KALP YETMEZLİGİNDE KULLANILIŞLARI]

Nurettin Özcan; Uğur Ural

doi:10.58600/eurjther.19930401-1159

Authors

Nurettin Özcan GATA ve Tıp Fak.İç Hastalıkları B.D.Prof.Dr.
Uğur Ural GATA ve Tıp Fak.İç Hastalıkları B.D.Uzm.

DOI:

https://doi.org/10.58600/eurjther.19930401-1159

Keywords:

.

Abstract

Severe acute and chronic heart failure refractory to the conventional regimen continues to be a leading cause of cardiac mortality. Because depression of myocardial contractility is an important pathophysiological factor of heart failure and because the cardiac glycosides possess a low therapeutic value, intense interest is focused on other non-glycoside, non-sympathomimetic positive inotropic agents. These new cardiotonic agents increase the force of action of phosphodiesterase properties and clinical values.

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