Gastrointestinal Symptoms and Autonomic Neutropathy in Diabetic Cases: [DİYABETES MELLİTUSLU OLGULARDA GASTROİNTESTİNAL SEMPTOMLAR VE OTONOMİK NÖROPATİ İLE İLİŞKİLERİ]

Yalçın Kepekçi; Can Boğa; Vahap Okan; Züheyr Günal

doi:10.58600/eurjther.19930401-1127

Authors

Yalçın Kepekçi Gaziantep Clniversitesi Tıp Fakültesi ; İç Hastalıkları ABD, Yrd. Doç.
Can Boğa Gaziantep Üniversitesi Tıp Fakültesi İç Hastalıkları ABD, Doç.
Vahap Okan Gaziantep Üniversitesi Tıp Fakültesi İç Hastalıkları ABD, Arş.Gör.Dr.
Züheyr Günal Gaziantep Üniversitesi Tıp Fakültesi İç Hastalıkları ABD, Arş.Gör.Dr.

DOI:

https://doi.org/10.58600/eurjther.19930401-1127

Keywords:

Diabetes mellitus, Autonomic neuropathy, Gastrointestinal complication

Abstract

Gastrointestinal symptoms and the relationship with the autonomic neutropathy on 120 diabetic patients were investigated 37 of the 120 diabetic patients (age range 34-75, mean 52.4±12.1) were male and the length of time since the diagnosis of diabetes m.allitus was 1-16 year (mean 7.2±6.8). There were gastrointestinal symptooms in 22.5 % of the 120 diabetic patients (two of 120 cases were type I diabetes mellitus). Night diarrhea in 9.4%, fecal incontinence in 1.7 %, signs of gastric atony in 1.7 % and constipation in 20% of these diabetic cases were observed. Autonoıriic test was performed in 34 diabetic patients, and autonomic neuropathy was determined in 35.2 % of them. it was observed that the diarrhea and gastric atony may be also associated with the autonornic neuropathy. Gall stones were determined in 7.5 % of the cases taken in the study.

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References

Jarpan JB. The neuropathies of diabetes. in De Groot LJ(eds): Endocrinology. V.11.Philadelphia: WB Sauders Co. 1989. ed 2 p.1490-1492.

Goyal RK. Spiro HM: Gastı:ointestinal manifestations of diabetes mellitus. Med Oin tıJorth Am 55: 1031-1044, 1971.

Unger RH, aFoster DW: Diabetic gastroenteropathy. in Foster D, Wilson J(eds): Williams textbook of endocrinology, Philadelphia : WB Sauders Co. 1985. ed 7 p.1053.

Vinnik IE, Kem F, Struthers JE: Mıılabsorpticin and the diarrhea of diabetes mellitus. Gastroenterology 43.507-520, 1962.

Wooten RL, Meriwether 1W: Diabetic gastric atony. A dinical study. JAMA 176:1082-1087, 1961.

Belvere WF, BoseUa G, Fededel D, et al : Diagnosis and management of diabetic autonomiic neuropathy. Br Med J. 187:61, 1983.

Page MB, Watkins PJ: Cardiorespiratuar arrest in diabetic autonomic neuropathy. Lancet Jan 7: 14, 1978.

Ewing DJ, Campbcu, Oarke BF. The natura! history of diabetic autonomic neuropathy. Q.ıaıt J Med 193; 95, 1980.

TaUey JN, Zinnmeister RA, Dyke VC, et al: Epidemiology of colonic symptoms and the irritable bowel syndrome. Gastroenterology 101; 927-934, 1991.

Schiller LR, Senta-Ana CA, SchmuUen AC, et al: Pathogenesis of fecal incontinence in diabetes mellitus. Evidence for internal anal-sphincter dysfunction. N. Eng J Med. 307; 1666-1671,1982.

Lieber MM: The incidence of gaUstones and their correlation with other diseases. Ann Surg 135: 394-405, 1952.

Zaher Z, Stemby NH, Kagen A, et al : Frequency of cholelithiasis in Praque a.nd Malmö, an autopsy study. Sc and J Gastroenterol 9: 3-7, 1974.