The Effects of EDTA, 8-Hydroxy Quinoline and Metal lons on the Serum Alkaline Phosphatase Activity Levels

Metin Gezici; Yüksel Özdemir

doi:10.58600/eurjther.1994-5-2-1012-arch

Authors

Metin Gezici Biyokimya Uzman Dr.,Zonguldak Devlet Hastanesi, Zonguldak
Yüksel Özdemir Gaziantep Üniversitesi Tıp Fakültesi Biyokimya ABD. Doç. Dr.

DOI:

https://doi.org/10.58600/eurjther.1994-5-2-1012-arch

Keywords:

Serum alkaline phosphatase, EDTA, 8-Hydroxy quinoline, Zn, Mg

Abstract

In this study, the inhibition effects of EDTA and 8-Hydroxy quinoline upon the serum alkaline phosphatase activity were examined. After this inhibition, the alkaline phosphatase activity level was decreased (% 90) using EDTA and (% 64) using 8-hydroxy quinoline. The alkaline phosphatase activity was restored with addition Zn and Mg ions after inhibition. Reactivation of alkaline phosphatase activity due addition of Zn was higher than Mg.

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