Clinical Management and Long-Term Follow-Up of Central Giant Cell Granulomas in the Jaw Bones: Case Reports and Treatment Outcomes


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DOI:

https://doi.org/10.58600/eurjther2776

Keywords:

central, giant cell granuloma, radiolucent lesion

Abstract

Central giant cell granulomas (CGCG) are benign jaw lesions most commonly found in dentate regions. They typically exhibit slow growth and appear as unilocular or multilocular radiolucencies on radiographic examination. Enucleation with curettage remains the treatment of choice; however, long-term follow-up is recommended due to the significant risk of recurrence. This report presents two cases of CGCG and discusses their clinical outcomes in relation to current literature.

References

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Figure 1. Clinical, Radiological, Surgical, and Histopathological Findings of a Central Giant Cell Granuloma Located in the Anterior Maxillary Region A: Intraoral clinical view of a well-defined radiolucent lesion located in the anterior maxilla. B: Post-surgical appearance following excision of the lesion and extraction of the adjacent teeth. C: Three-dimensional computed tomography image of the maxilla within the craniofacial skeleton. D: Histopathological image showing multinucleated giant cells situated within a vascularized fibrous connective tissue containing numerous hemorrhagic foci and hemosiderin pigment.

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Published

2025-09-23

How to Cite

Akay, B., Kırdemir, M., Dindar, K., & Koca, H. (2025). Clinical Management and Long-Term Follow-Up of Central Giant Cell Granulomas in the Jaw Bones: Case Reports and Treatment Outcomes. European Journal of Therapeutics, 31(5), 360–364. https://doi.org/10.58600/eurjther2776

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Letter to the Editor