ISSN 2564-7784 | E-ISSN 2564-7040
Original Article
One of every three cases of infective endocarditis followed in our center is Brucella endocarditis
1 Harran Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, Şanlıurfa  
2 Harran Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisi Anabilim Dalı, Şanlıurfa  
3 Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey  
Eur J Ther 2013; 19: 103-107
DOI: 10.5455/GMJ-30-2013-136
Key Words: Brucella endocarditis; infective endocarditis
Abstract

The purpose of this study is to determine the epidemiological, clinical and laboratory characteristics and prevalence of Brucella endocarditis followed in our hospital was. The study were included 24 infective endocarditis (EE) patients (12 female, 12 male, mean age, 41.3 years, range, 12-85 years) followed in our clinic between 2008-2012 and diagnosed with modified Duke criteria. The demographic, clinical, echocardiographic, laboratory variables, treatment and follow-up data were evaluated. EE was associated with in 20 patients (83.3%), natural valve, 4 (12.2%), mechanical prosthetic valve and 1 patient (4.2%) a permanent pacemaker. Among natural valves, mitral valve was the most frequently involvement (45% of mitral, aortic 35%, tricuspid valve 10%). Mitral valve was most commonly affected prosthetic valves (100%). The most common symptoms included fever (66.7%), chills and sweating (37.5%), fatigue (12.5%). Vegetation was the most common lesion (66.6%) in transthoracic and/or transesophageal echocardiography. In bacterial cultures, brucella were isolated the most common bacteria (33%). Staphylococcus (21%) and Streptococcus (17%) was positive in cultures and in 5 (20.8%) cases were culture negative. Nine patients (37.4%) underwent surgical treatment. 50% of the native aortic valve, aortic valve replacement 12.5%, 25% and 12.5% of the prosthetic mitral valve and native mitral valve was patients with the diagnosis of brucellosis. Clinical signs of brucella endocarditis were similar with EE. Surgery and medical treatment are the most commonly used treatment in brucella endocarditis. Young age (mean age, 38.9 years), aortic involvement (62.5%), native valve involvement (62.5%), prolonged incubation period (average 10 days) were features of Brucella endocarditis. The characteristics of EE showed similar to literature results. At our center 1/3’s EE patients were seen due to Brucella bacteries. Brucella endocarditis should be considered features young age, aortic involvement, native valvuler involvement and long incubation period. 

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