European Journal of Therapeutics
Original Article

Subclinical Coronary Atherosclerosis in Patients Undergoing Catheter Ablation for Idiopathic Premature Ventricular Complexes

1.

Department of Cardiology, Hacettepe University School of Medicine, Ankara, Turkey

2.

Department of Cardiology, Eskisehir Osmangazi University School of Medicine, Eskisehir, Turkey

3.

Department of Biostatistics, Hacettepe University School of Medicine, Ankara, Turkey

Eur J Ther 2020; 26: 245-250
DOI: 10.5152/eurjther.2020.20058
Read: 50 Downloads: 70 Published: 22 September 2020

Objective: Idiopathic premature ventricular complexes (PVC) occur in the absence of clinically apparent structural heart disease (SHD) and are treated effectively with catheter ablation. We aimed to evaluate the association of PVC characteristics with subclinical coronary artery disease (CAD) during catheter ablation.

Methods: A total of 116 patients (age: median 55 years; sex: 58.6% men), without SHD, in whom PVC ablation and coronary angiography had been performed simultaneously were enrolled. PVC localizations were categorized into 4 groups as; right ventricular outflow tract (RVOT), left ventricular outflow tract (LVOT), left ventricle (LV)-body, and right ventricle (RV)-body. PVC frequency was also classified as moderate (5,000–10,000 PVCs/day) and frequent (≥10,000 PVCs/day). Coronary artery stenoses were categorized as normal, non-critical (<50%), and critical (≥50%).

Results: Co-incidental CAD was more frequent among patients with LV-body originated PVCs (non-critical, 51.6 % and critical, 22.6 %); while most of the patients with LVOT, RVOT, and RV-body originated PVCs had normal coronary arteries (58.8%, 56%, and 55.6%, respectively; p=0.019). There was no significant association between PVC frequency and coronary artery lesion severity (p=0.080) or between PVC recurrence and PVC frequency (p=0.748), PVC localization (p=0.188), coronary artery lesion severity (p=0.080), number of involved coronary artery segments (p=0.566), and number of involved coronary artery vessels (p=0.729).

Conclusion: Subclinical CAD was more frequent among patients with LV-body originated idiopathic PVCs. Thus, its routine pre-procedural assessment may be considered for LV-body originated PVCs.

How to cite: Ateş AH, Yorgun H, Canpolat U, Dural M, Şener YZ, Oksul M, et al. Subclinical Coronary Atherosclerosis in Patients Undergoing Catheter Ablation for Idiopathic Premature Ventricular Complexes. Eur J Ther 2020; 26(3): 245-50.

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