European Journal of Therapeutics
Original Article

Remission Rates, Time to Remission, and Related Factors in Adolescents with Major Depressive Disorder

1.

Department of Child and Adolescent Psychiatry, Gaziantep University School of Medicine, Şahinbey Research and Practice Hospital, Gaziantep, Turkey

2.

Department of Child and Adolescent Psychiatry, Abant _Izzet Baysal University Faculty of Medicine, Bolu, Turkey

3.

Department of Child and Adolescent Psychiatry, Yıldırım Bayezit University, Ankara, Turkey

4.

Department of Child and Adolescent Psychiatry, Ordu University Training & Research Hospital, Ordu, Turkey

5.

Department of Child and Adolescent Psychiatry, Acıbadem Mehmet Ali Aydınlar University, _Istanbul, Turkey

Eur J Ther 2021; 27: 219-223
DOI: 10.5152/eurjther.2021.20081
Read: 88 Downloads: 43 Published: 29 September 2021

Objective: Major depressive disorder (MDD) is a common disorder in children and adolescents that can cause serious morbidity and mortality. Although response rates to treatment are high, less than half of the adolescents with MDD achieve remission. The present study aims to evaluate remission rates, time to remission, and the predictors of remission in adolescents with MDD.

Methods: This study included 34 adolescents with MDD who were followed-up for a minimum period of 120 days. The adolescents were assessed with the Clinic Global Impression Scale, Beck Depression Inventory, Young Mania Rating Scale, Child Mania Rating Scale, and Screen for Child Anxiety-Related Emotional Disorders at the baseline and at weeks 4, 8, and 12.

Results: 67.6% of the adolescents had at least one comorbid diagnosis. The remission rate at week 12 was 73.5%. The mean time to remission was 72.0 days. The female adolescents achieved a significantly higher remission rate than the males.

Conclusion: The majority of adolescents achieved remission following acute treatment, and that the time to remission for the female adolescents was shorter compared with the males. Remission time does seem neither to be related to the number of medications prescribed nor to the number of comorbid diagnoses.

How to cite: Topal Z, O¨ ztu¨rk Y, Demir N, Adıgu¨zel O¨ , Karadag˘ M, Tufan AE. Remission Rates, Time to Remission, and Related Factors in Adolescents with Major Depressive Disorder. Eur J Ther 2021; 27(3): 219-223.

Files
EISSN 2564-7040