European Journal of Therapeutics
Original Article

Malignant Transformation of Mature Cystic Teratomas: A Retrospective Analysis of 181 Cases

1.

Department of Pathology, University of Gaziantep, Gaziantep, Turkey

2.

Department of Obstetrics and Gynecology, University of Gaziantep, Gaziantep, Turkey

Eur J Ther 1; 1: -
DOI: 10.5152/EurJTher.2019.190108
Read: 124 Downloads: 58 Published: 16 December 2019

Introduction: Mature cystic teratoma (MCT) comprises 20% of all ovarian tumors and is the most prevalent ovarian germ cell tumor. Any of its component tissues may undergo a malignant transformation (MT). This study aims to retrospectively analyze the malignancies that arise from MCT of the ovary.

Materials and Methods: Histopathological diagnoses of resection materials obtained from adult patients who were operated for an ovarian mass and diagnosed by our laboratory between January 2012 and December 2018 were reviewed.


Results: Of our one-hundred-and-eighty-one (181) cases, seven (3.86%) were detected to have MT. Of our cases with MT; 5 had papillary thyroid carcinoma, 1 had squamous cell carcinoma, and 1 had a strumal carcinoid.


Conclusion: The diagnosis of malignancies arising from MCT is important for the identification of follow-up and treatment options for the patients. Reporting the data obtained from cases who demonstrate MT will be informative for the pre/postoperative management of the patients.

How to cite: Bozdağ Z, Bayramoğlu Tepe N. Malignant Transformation of Mature Cystic Teratomas: A Retrospective Analysis of 181 Cases. Eur J Ther 2019; DOI: 10.5152/EurJTher.2019.190108

Files
ISSN2564-7784 EISSN 2564-7040