European Journal of Therapeutics
Review

HLA-G with Benefits and Damages: A Review

1.

Department of Medical Biology and Genetics, Izmir Katip Celebi University School of Medicine, İzmir, Turkey

2.

Medical Sciences University, Tepecik Traning and Research Hospital, Tissue Typing Laboratory, İzmir, Turkey

Eur J Ther 2020; 26: 138-142
DOI: 10.5152/EurJTher.2019.18063
Read: 19 Downloads: 10 Published: 29 June 2020

Human leucocyte antigen-G (HLA-G) is a non-classical HLA that researchers primarily focused on association with the complications of pregnancy. Recent studies about the immunomodulatory characteristics of HLA-G showed that this molecule is not only important in pregnancy but also have effects on transplantation, autoimmune diseases, cancer and infectious diseases. The restricted polymorphic nature and the disease association has also showed in various studies. In this review it was aimed to evaluate the benefits and damages of the HLA-G by considering both the expression levels and polymorphisms.

How to cite: Department of Medical Biology and Genetics, Izmir Katip Celebi University School of Medicine, İzmir, Turkey

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ISSN2564-7784 EISSN 2564-7040