EISSN 2564-7040

INDEXED IN WEB OF SCIENCE AND TUBITAK ULAKBIM TR INDEX

European Journal of Therapeutics

27 70 2021

HIGHLY CITED ARTICLES

How Should Helicobacter Pylori Eradication Be Performed in Cases of Extensive Allergies to Proton Pump Inhibitors?

By: Sahin, Yasin; Yilmaz, Ozlem

Drug Resistance in Parasitic Diseases

By: Ertabaklar, Hatice; Malatyali, Erdogan; Ertug, Sema

Radioprotective Effect of Caffeic Acid Phenethyl Ester on the Brain Tissue in Rats Who Underwent Total-Head Irradiation

By: Khayyo, Nesrin; Taysi, Muhammed Enes; Demir, Elif; et al.

The Efficacy of Pneumatic Compression Devices in the Treatment of Patients with Lymphedema after Mastectomy

By: Duymaz, Tomris

Effects of Gabapentin on Carrageenan-Induced Inflammation, Acute Phase Reactants and Gastric Mucus Secretion in Rats

By: Kilic, Fatma Sultan; Aydin, Sule; Yildirim, Cafer; et al.

Unusual Presentation of Bilaterally Symmetrical Gout Tophi on Elbows

By: Kekec, Ahmet Fevzi; Bozgeyik, Bilgin; Yilmaz, Selcuk

Original Research

Estimation of Salivary and Tissue Nitric Oxide Levels in Oral Squamous Cell Carcinoma: A Biochemical Study

Rumela Ghosh ¹ , Renita Lorina Castelina ² , Subhas G. Babu ² , Baishwanar Banerjee ³

Author Affiliation(s)

1.

Ivory Dental Clinic, Bangkok, Thailand

2.

Department of Oral Medicine and Radiology, Nitte University, A B Shetty Memorial Institute of Dental Sciences, Mangalore, India

3.

Department of forensic medicine and toxicology, Manipal University School of Medicine, Manipal, India

Eur J Ther 2021; 27: 26-31

DOI: 10.5152/eurjther.2021.20039

Keywords : Oral cancer, nitric oxide, malignancy, neoplasm

Read: 183 Downloads: 27 Published: 30 July 2020

Volume 27, Issue 1, March 2021

Previous Article

Objective: The study was conducted to estimate the salivary and tissue nitric oxide (NO) levels in healthy individuals and subjects with squamous cell carcinoma of the oral cavity.

Methods: In this study, the salivary and tissue NO levels were estimated in 20 healthy subjects and 20 patients with oral squamous cell carcinoma (OSCC).

Results: The mean salivary NO levels in Group I (control group) was 78.59 µM/L (standard deviation=5.91608), while the mean salivary NO levels of Group II (study group) were 115.6765 µM/L (standard deviation=0.9431). The mean tissue NO levels in Group I (control group) was 87.6315 µM/L (standard deviation=1.91631), while the mean tissue NO of Group II (study group) was 172.376 µM/L (standard deviation=0.84774.

Conclusion: Our results illustrated that the increase in the NO levels in the saliva is positively correlated with the NO level in tissues; hence, salivary NO level can be used as a potential diagnostic biomarker in OSCC.

How to cite: Ghosh R, Castelino RL, Babu SG, Banerjee B. Estimation of Salivary and Tissue Nitric Oxide Levels in Oral Squamous Cell Carcinoma: A Biochemical Study. Eur J Ther 2021; 27(1): 26-31.

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