European Journal of Therapeutics
Original Article

Comparison of Success Rates of Pleurodesis with Talc, and Holmium-YAG Laser in the Patients with Malignant Pleural Effusion

1.

Department of Thoracic Surgery, Gaziantep University School of Medicine, Gaziantep, Turkey

2.

Clinic of Thoracic Surgery, Dr. Ersin Arslan State Hospital, Gaziantep, Turkey

3.

Clinic of Thoracic Surgery, Ankara Güven Hospital, Ankara, Turkey

4.

Department of Biostatistics, Gaziantep University School of Medicine, Gaziantep, Turkey

5.

Clinic of Chest Diseases, Acibadem Taksim Hospital, İstanbul, Turkey

6.

Clinic of Thoracic Surgery, Medicalpark Hospital, Gaziantep, Turkey

Eur J Ther 2019; 25: 115-120
DOI: 10.5152/EurJTher.2018.623
Read: 406 Downloads: 85 Published: 03 September 2019

Abstract

 

Objective: We aimed to investigate the efficacy of Holmium-yttrium aluminum garnet (Ho-YAG) laser using video assisted thoracoscopic surgery (VATS) and compare it with the talcslurry pleurodesis in patients with malignant pleural effusion (MPE).

 

Methods: A total of 51 patients with MPE were included. Patients were divided into two groups. In the laser group, pleurodesis was attempted using Ho-YAG laser through auniportal VATS in 30 patients; in the talc group, pleurodesis was attempted using talc slurry through a small bore chest tube in 21 patients. The success rate of pleurodesis was evaluated using chest X-ray and/or thorax computed tomography obtained at the second month following pleurodesis and was graded as total success, partial success, or failure.

 

Results: In the laser group, pleurodesis was a total success in 19 (63%) patients and partial in 7 (23%) patients. The volume of pleural effusion drained postoperatively was significantly different between the success subgroups (total success subgroup vs. failure subgroup, p=0.000; partial success subgroup vs. failure subgroup, p=0.001). In the talc group, pleurodesis was a total success in 11 (52%) patients and partial in 6 (29%) patients. The success rates of pleurodesis between the talc and laser groups showed no significant difference (p=0.725).

 

Conclusion: The use of Ho-YAG laser through VATS is a safe and effective option for pleurodesis in the management of MPE. However, there is no difference between Ho-YAG laser and talc slurry pleurodesis in terms of procedure success rates.

 

How to cite: Uluşan A, Şanlı M, Arslan E, Işık AF, Tunçözgür B, Kul S, et al. Comparison of Success Rates of Pleurodesis with Talc, and Holmium-YAG Laser in the Patients with Malignant Pleural Effusion. Eur J Ther 2019; 25(2): 115-20.

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ISSN2564-7784 EISSN 2564-7040