ISSN 2564-7784 | E-ISSN 2564-7040
Original Article
Evaluation of Hypertension-Related Mortality in the Turkey, 2000-2014.
1 Department of Biostatistics and Medical Informatics, Afyon Kocatepe University School of Medicine, Afyonkarahisar, Turkey  
Eur J Ther ; : -
DOI: 10.5152/EurJTher.2018.476
Key Words: Hypertension, mortality rate, joinpoint regression analysis, age-period-cohort analysis
Abstract

 

Objective: Hypertension continues to be a leading risk factor for cardiovascular disease and mortality worldwide. The purpose of the study is to analyze the long term trends of hypertension mortality in Turkey between 2000-2014 (for male and female).


Methods
: Analyses were based on Hypertension mortality from Turkish Statistical Institute death database. Analyses were based upon hypertension mortality data obtained from the Turkish Statistical Institute. Age-standardized mortality rates were calculated using direct standardization for each calendar year.  We estimated the age-adjusted linear trend for annual percent change (APC) and average annual percent change (AAPC) with the corresponding 95% confidence interval (CI) using the joinpoint regression analysis. Furthermore, we conducted an age-period-cohort analysis to quantify recent time trends and to evaluate the significance of cohort and period effects. We were carry out age-period-cohort analysis to measure the quantity of recent trends and to evaluate the significance of cohort and period effects.


Results
: During the study period It is observed that a significant upward trend in the mortality of hypertension in Turkey (AAPC=2.7%, 95% CI 1.9%-3.4%). The trend of hypertension mortality has increased both in male(AAPC=7.4%, 95% CI 3.0%-11.9%) and female (AAPC=8.7%, 95% CI 4.1%-13.5%). We found that the net drift was 2.1% (95% CI 0.6%-3.6%) per year for male and 2.0% (95% CI 0.4%-3.7%) per year for female. According to longitudinal age curves, the mortality of hypertension increased with age both male and female. The period and cohort effects are highly significant both male and female.


Conclusion
: Hypertension is one of the leading causes of mortality causing cardiovascular disease (CVD). Knowing the risk factors and preventive methods could help to reduce the hypertension related mortalities. 

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