ISSN 2564-7784 | E-ISSN 2564-7040
Case Report
Diabetic ketoacidosis occurring in the patient whom newly started ınsulin Glargine U300
1 Department of Endocrinology and Metabolism, Selçuk University School of Medicine, Konya, Turkey  
Eur J Ther ; : -
DOI: 10.5152/EurJTher.2017.293
Key Words: Glargine U300, diabetic ketoacidosis, pharmacokinetic
Abstract

 

Insulin glargine U300 is a 3-fold concentrated long-acting insulin analog compared to insulin glargine U100. However, reaching the stable plasma insulin concentration occurs on day 4 of the treatment. Patients with type 1 and type 2 diabetes mellitus who has decreased insulin reserve are at increased risk of diabetic ketoacidosis when there is insufficient exogenous plasma insulin concentration. In this case, a case of diabetic ketoacidosis occuring in a patient with insulin glargine U300 was presented and the pharmacokinetic properties of insulin glargine U300 were emphasized.

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