ISSN 2564-7784 | E-ISSN 2564-7040
Original Article
Relationship Between Renal Resistive Index and Increased Renal Cortical Stiffness in Patients with Preserved Renal Function
1 Department of Radiology, University of Health Sciences-Adana Health Practice and Research Center, Adana, Turkey  
2 Department of Internal Medicine, University of Health Sciences-Adana Health Practice and Research Center, Adana, Turkey  
Eur J Ther 2018; 24: 255-261
DOI: 10.5152/EurJTher.2018.817
Key Words: Conventional ultrasonography, cortical stiffness, renal resistive index

Objective: We aimed to investigate the relationship between cortical stiffness (CS) determined by shear wave elastography (SWE) and conventional ultrasonography (USG) parameters, and identify the determining parameters that increased CS.


Methods: In this study, 229 patients who underwent renal USG were included. In addition to conventional renal USG, SWE was performed. Patients were divided into two groups: with increased CS and without increased CS.


Results: The median CS value of the patients included in the study was 4.92 kPa. The increased CS value was taken as the limit value of 5.0 kPa. The age, creatinine and estimated glomerular filtration rate levels, and presence of diabetes and hypertension were significantly higher in the increased CS group (p<0.05). It was found that the cortical echogenicity increase (stage I-II), renal resistance index (RRI), and acceleration time values were significantly higher in patients with increased CS (p<0.05). When logistic regression analysis was performed to identify patients with increased CS, we found that RRI, diabetes presence, and cortical echogenicity stages I and II independently predicted an increase in CS (p<0.05). According to this analysis, RRI (every-0.1), diabetes, and cortical echogenicity stages I and II increased the risk of increased CS by 2.3 times, 14%, 10.5% and 18.2%, respectively. In ROC analysis for RRI, the area under the curve was 0.719. When the cut-off value for RRI was taken as 0.70, it was found to be 71.1% sensitive and 64.3% specific for increased CS.


Conclusion: The increase in renal echogenicity and RRI obtained by conventional USG studies independently identifies patients with increased CS.

Key Words
AVES | Copyright © 2018 European Journal of Therapeutics | Latest Update: 11.03.2019